THE EFFECT OF TRANSDERMAL SCOPOLAMINE ON THE INCIDENCE AND SEVERITY OF POSTOPERATIVE NAUSEA AND VOMITING IN A GROUP OF HIGH-RISK PATIENTS GIVEN PROPHYLACTIC INTRAVENOUS ONDANSETRON

AANA Journal | April 1, 2006| | Copyright

Specific risk factors place patients at greater risk for postoperative nausea and vomiting (PONV). Routinely, these patients are treated prophylactically with intravenous (IV) ondansetron or transdermal (TD) scopolamine. No study has examined what effect using a combination of these prophylactic treatments would have on the incidence of PONV in a group of high-risk patients.

A total of 56 patients at high risk for PONV were treated prophylactically with IV ondansetron and randomized to receive a TD scopolamine patch or placebo. Demographics, incidence, and severity of PONV and side effects ...

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