Determination of the Antihypertensive Peptide LHLPLP in Fermented Milk by High-Performance Liquid Chromatography-Mass Spectrometry

From: Journal of Dairy Science | Date: December 1, 2006| Author: Delgado, M A; Et al; Muguerza, B; Ramos, M; ³ Quirà s, A | Copyright information

ABSTRACT

Among different lactic acid bacteria isolated from raw milk, 4 Enterococcus faecalis strains have stood out as producers of fermented milk with potent antihypertensive activity. The peptide β-casein f(133-138), LHLPLP, was identified as one of the major peptides responsible for the activity of these fermented milk products. A simple method was developed to quantify this peptide in fermented milk using high-performance liquid chromatography coupled in line with mass spectr...

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