PRESENT AND FUTURE BIOCHEMICAL MARKERS FOR DETECTION OF ACUTE CORONARY SYNDROME From: Critical Reviews in Clinical Laboratory Sciences | Date: September 1, 2006| Author: Pettersson, Kim; Wittfooth, Saara; Eriksson, Susann | Copyright Taylor & Francis Ltd. 2006. Provided by ProQuest LLC.Copyright information

The use of biochemical markers in the diagnosis and management of patients with acute coronary syndrome has increased continually in recent decades. The development of highly sensitive and cardiac-specific troponin assays has changed the view on diagnosis of myocardial infarction and also extended the role of biochemical markers of necrosis into risk stratification and guidance for treatment. The consensus definition of myocardial infarction places increased emphasis on cardiac marker testing...

Related newspaper, magazine, and journal articles from HighBeam Research

	Selection of Antibodies and Epitopes for Cardiac Troponin Immunoassays: Should We Revise Our Evidence-Based Beliefs? Clinical Chemistry ; Cardiac troponins are regarded as the most specific and sensitive of the currently available diagnostic techniques for detection of myocardial damage, and the redefined criteria used to classify acute coronary syndrome patients presenting with ischemic symptoms as myocardial infarction patients are
	The Interfering Component in Cardiac Troponin I Immunoassays: Need for Further Experimental Evidence Clinical Chemistry ; To the Editor: I read with great interest the report by Eriksson et al. (1), discussing the existence of a frequently occurring blood component that interferes with immunoassays measuring cardiac troponin I (cTnI) by use of antibodies against epitopes in the central part of the molecule. As a main
	Plasma 99th Percentile Reference Limits for Cardiac Troponin and Creatine Kinase MB Mass for Use with European Society of Cardiology/American College of Cardiology Consensus Recommendations Clinical Chemistry ; Background: The European Society of Cardiology/American College of Cardiology (ESC/ACC) consensus document for definition of myocardial infarction (MI) is predicated on increased cardiac troponin or creatine kinase (CK) MB mass above the 99th percentile reference limit. The purpose of this study
	Clinical Chemistry through Clinical Chemistry: A Journal Timeline Clinical Chemistry ; ... gene mutations by using primer oligo base extension and mass spectrometry. Clin Chem 1997;43:1151-8. The world reels from the news of Princess Diana's death. Hong Kong returns to Chinese rule. Nobel Prizes in Chemistry are awarded to Paul D. Boyer, Jens C ...
	Evaluation of Imprecision for Cardiac Troponin Assays at Low-Range Concentrations Clinical Chemistry ; Background: The European Society of Cardiology/ American College of Cardiology Committee for the Redefinition of Myocardial Infarction (MI) has recommended that an increased cardiac troponin should be defined as a measurement above the 99th percentile value of the reference group. A total
	PRESENT AND FUTURE BIOCHEMICAL MARKERS FOR DETECTION OF ACUTE CORONARY SYNDROME Critical Reviews in Clinical Laboratory Sciences ; The use of biochemical markers in the diagnosis and management of patients with acute coronary syndrome has increased continually in recent decades. The development of highly sensitive and cardiac-specific troponin assays has changed the view on diagnosis of myocardial infarction and also extended
	Beliefs in Cardiac Troponin Testing Clinical Chemistry ; To the Editor: In a recent editorial, Panteghini (1) asks whether there is a need to revise evidence-based beliefs regarding the currently recommended design of troponin immunoassays as a consequence of our recent and previous reports (2-4) on the occurrence of circulating anti-troponin antibodies,
	Coronary angiographic findings in patients with clincal unstable angina according to cardiac troponin I and T concentrations in serum: A comparative analysis Archives of Pathology & Laboratory Medicine ; * Context.-Elevated cardiac troponin levels have been reported to identify unstable angina patients at high risk. Objective.-To examine the relation of cardiac troponin I (cTnI) and cardiac troponin T (cTnT) levels to findings of coronary angiography in these patients. Methods.-Samples for troponin
	Validation of the 99th Percentile Cutoff Independent of Assay Imprecision (CV) for Cardiac Troponin Monitoring for Ruling Out Myocardial Infarction Clinical Chemistry ; By definition, the probability that a single measured cardiac troponin result exceeds the estimated 99th percentile is equal to 0.01 (1%) for a person randomly selected from the general (reference) population. This is irrespective of the imprecision profile of the analytical method as well as the
	Innotrac Aio! Second-Generation Cardiac Troponin I Assay: Imprecision Profile and Other Key Characteristics for Clinical Use Clinical Chemistry ; To the Editor: Cardiac troponin has been designated as the preferred biomarker for diagnosis of myocardial infarction (MI) (1). Previously published data, however, confirm the large diversity among cardiac troponin assays with respect to important analytical characteristics, including assay

See all results.