Tissue microarray: An effective high-throughput method to study the placenta for clinical and research purposes

Journal of Maternal - Fetal & Neonatal Medicine | August 1, 2006| | Copyright

Abstract

Objective. Tissue microarray (TMA) technology allows simultaneous examination of the expression of many molecular markers (protein, mRNA, DNA, etc.) with high-throughput. The application of this technology, to date, has been largely confined to the study of cancer. Placental pathology poses unique challenges because of the size of the organ, its complex anatomy, as well as its histological heterogeneity. The objective of mis study was to assess the feasibility and efficiency of TMAs for immunohistochemistry and in situ hybridization of placental tissues.

Study design. TMAs were ...

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Tissue microarray: An effective high-throughput method to study the placenta for clinical and research purposes
Magazine article from: Journal of Maternal - Fetal & Neonatal Medicine ; ...Objective. Tissue microarray (TMA) technology...with high-throughput. The application...placental tissues. Study design...automated tissue arrayer...showed the highest agreement...practical and effective tool for...the human placenta. Duplicate...with ...

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