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Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: Modulation by glucocorticoids and beta-agonists
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Recent studies have demonstrated that tumor necrosis factor (TNF)-alpha stimulates the secretion of interleukin (IL)-6 and regulated on activation, normal T cells expressed and secreted (RANTES) from airway smooth muscle (ASM) cells, with the induction of each molecule being differentially regulated (IL-6 increased, RANTES inhibited) by cyclic adenosine monophosphate (cAMP)-elevating agents. In this study we identify the mechanisms mediating IL-6 and RANTES gene transcription in human ASM cel...
Related newspaper, magazine, and journal articles from HighBeam Research
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Gene expression: better tools: more complex results.(Cover story)
Bioscience Technology
; Gene expression has become a mainstream technique in biology, medicine, and drug development. Broadly speaking, gene expression comes in two flavors: analytical and functional. The former refers to detecting and quantifying genes, especially by comparing two samples (treated/untreated,
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Universal RNA Reference Materials for Gene Expression
Clinical Chemistry
; A workshop entitled "Metrology and Standards Needs for Gene Expression Technologies: Universal RNA Standards" was held in March 2003 to define the requirements for standardizing RNA-based molecular assays, specifically microarray and quantitative reversetranscriptase-PCR technologies. NIST
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Gene expression, neurogensis, and healing: Psychosocial genomics of therapeutic hypnosis
American Journal of Clinical Hypnosis
; The historical lineage of therapeutic hypnosis in James Braid's "psychophysiology", Pierre Janet's "physiological modification", and Milton Erickson's "neuro-psycho-physiology" is extended to include current neuroscience research on activity-dependent gene expression, neurogenesis, and stem cells
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Tackling High Variability in Gene Expression Studies.
Genomics and Proteomics
; By Juan Pedro Steibel, Steven P. Suchyta, and Guilherme J. M. Rosa High variability in gene expression studies often prevents differences from being noticed. To increase power and improve precision of such experiments, special attention should be given to each source of variation functioning in the
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Symposium: Calorie restriction: Effects on body composition, insulin signaling and aging--microarray profiling of gene expression in aging and its alteration by caloric...
The Journal of Nutrition
; Microarray Profiling of Gene Expression in Aging and Its Alteration by Caloric Restriction in Mice 12 ABSTRACT An active research area in biological gerontology concerns the mechanisms by which caloric restriction (CR) retards the aging process in laboratory rodents. We used high density
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Digital Gene Expression Profiling by Serial Analysis of Gene Expression
American Journal of Respiratory Cell and Molecular Biology
; During recent years there has been intense interest directed toward high throughput transcript profiling involving the acquisition of molecular "snapshots" of eukaryotic gene expression levels. This has allowed rapid association of characterized and uncharacterized genes with a given disease
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Adding Confidence to Gene Expression Clustering
Genetics
; ... means clustering (TAVAZIOE et al. 1999) and self-organizing maps (TAMAYO et al. 1999), or nested, as with hierarchical clustering ... Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. Proc ...
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Genomic Survey of Gene Expression Diversity in Arabidopsis thaliana
Genetics
; ABSTRACT Differential gene expression controls variation in numerous plant traits, such as flowering time and plant/ pest interactions, but little is known about the genomic distribution of the determinants of transcript levels and their associated variation. Affymetrix ATH1 GeneChip microarrays
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High-Throughput, High-Sensitivity Analysis of Gene Expression in Arabidopsis1[W][OA]
Plant Physiology
; ... Strachan T, Abitbol M, Davidson D, Beckmann JS (1997) A new dimension for the human genome project: towards comprehensive expression maps. Nat Genet 16:126-132 Takahashi S, Seki M, lshida J, Satou M, Sakurai T, Narusaka M, Kamiya A, Nakajima M1 Enju A, Akiyama K ...
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Gene Expression Profiling in Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine
; The launch of the human genome project and the development of gene expression profiling analyses at nearly the same time have had a dramatic effect on scientific inquiry in the molecular basis of human diseases. Previously, when one wished to study the effect of a disease process or environmental
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