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Selected Traditional Structural Descriptors and R^sub M^ Values for Estimation and Prediction of Lipophilicity of Homologous Series of Saturated Fatty Acids
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ABSTRACT:
An homologous series of carboxylic FA, from methanoic to triacontanoic, were characterized by selected structural descriptors based on distance matrix (W, A, ^sup 0^B, ^sup 1^B), adjacency matrix (M, M^sup ν^, ^sup 0^χ, ^sup 1^χ, ^sup 2^χ, ^sup 0^χ^sup ν^, ^sup 1^χ^sup ν^, ^sup 2^χ^sup ν^, F, N^sub 2^), and information theory (I^sub SA^, ...) as well as electrotopological states. Saturated FA, from pentanoic to eicosanoic as well as from heptanoic to tricontanoic acids, were separated by reversed-phase high-performance TLC (RP-HPTLC) ...
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Pharmacokinetics and Biodistribution of ^sup 111^In- and ^sup 177^Lu-Labeled J591 Antibody Specific for Prostate-Specific Membrane Antigen: Prediction of ^sup 90^Y-J591 Radiation Dosimetry Based on ^sup 111^In or ^sup 177^Lu?
; ^sup 111^In-Labeled antibodies and peptides have...used as chemical and biologic surrogates for ^sup 90^Y-labeled therapeutic agents. However, recent...significant differences in biodistribution between ^sup 111^In- and ^sup 90^Y-labeled agents. Yttrium...
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Effects of Intracellular and Extracellular Concentrations of Ca^sup 2+^, K+, and Cl- on the Na+-Dependent Mg^sup 2+^ Efflux in Rat Ventricular Myocytes
; ABSTRACT Intracellular Mg^sup 2+^ concentration ([Mg^sup 2+^]^sub i^) was measured in rat ventricular myocytes with...indicator furaptra (25C). After the myocytes were loaded with Mg^sup 2+^, the initial rate of decrease in [Mg^sup 2+^]^sub i^ (initial...
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Processing of Generator-Produced ^sup 68^Ga for Medical Application
; The ^sup 68^Ge/^sup 68^Ga generator provides an excellent source of positron-emitting ^sup 68^Ga. However, newly available "ionic" ^sup 68^Ge/^sup 68^Ga radionuclide generators are not necessarily optimized for the synthesis of ^sup 68^Ga-labeled...
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Low-Affinity Na^sup +^ Uptake in the Halophyte Suaeda maritima1[C][W][OA]
; Na^sup +^ uptake by plant roots has largely been explored using species that accumulate little Na^sup +^ into their shoots. By way of contrast, Nathe...its leaves. Here we report that cAMP and Ca^sup 2+^ (blockers of nonselective cation channels...
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^sup 99m^Tc-N-DBODC5, a New Myocardial Perfusion Imaging Agent with Rapid Liver Clearance: Comparison with ^sup 99m^Tc-Sestamibi and ^sup 99m^Tc-Tetrofosmin in Rats
; ^sup 99m^Tc-[bis (dimethoxypropylphosphinoethyl)-ethoxyethylamine (PNP5...myocardial uptake and clearance kinetics and organ biodistribution of ^sup 99m^Tc-N-DBODC5 with ^sup 99m^Tc-sestamibi and ^sup 99m^Tc-tetrofosmin. Methods: Seventy-five...
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Comparison of ^sup 123^I and ^sup 131^I for Whole-Body Imaging in Thyroid Cancer
; We compared the diagnostic sensitivities of ^sup 123^I and ^sup 131^I whole-body imaging in differentiated thyroid cancer...thyroidectomized patients (3 previously treated with ^sup 131^I) were studied. After a period of thyroid hormone...
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Arabidopsis HMA2, a Divalent Heavy Metal-Transporting P^sub IB^-Type ATPase, Is Involved in Cytoplasmic Zn^sup 2+^ Homeostasis1
; P^sup IB^-type ATPases transport heavy metal ions (Cu^sup +^, Cu^sup 2+^, Zn^sup 2+^, Cd^sup 2+^, Co^sup 2+^, etc.) across biological membranes. Several members of this subfamily are present in plants. Higher plants are the only eukaryotes where putative...
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Skeletal PET with ^sup 18^F-Fluoride: Applying New Technology to an Old Tracer*
; Although ^sup 18^F-labeled NaF was the first widely used...fell into disuse after the introduction of ^sup 99m^Tc-labeled bone-imaging agents. Recent comparative studies have demonstrated that ^sup 18^F-fluoride PET is more accurate than ^sup...
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Treatment with ^sup 177^Lu-DOTATOC of Patients with Relapse of Neuroendocrine Tumors After Treatment with ^sup 90^Y-DOTATOC
; Therapy with [^sup 90^Y-DOTA^sup 0^, Tyr^sup 3^]-octreotide (DOTATOC, where DOTA = tetraazacyclododecane tetraacetic acid and TOC = D-Phe-c(Cys-Tyr-D-Trp-Lys-Thr-Cys)-Thr(ol)) is established for the treatment of metastatic neuroendocrine tumors. Nevertheless...
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Differential Uptake of O-(2-^sup 18^F-Fluoroethyl)-L-Tyrosine, L-^sup 3^H-Methionine, and ^sup 3^H-Deoxyglucose in Brain Abscesses
; The amino acid O-(2-^sup 18^F-fluoroethyl)-L-tyrosine (^sup 18^F-FET) has been shown to be a useful tracer for brain tumor imaging. Experimental studies demonstrated no uptake of ^sup 18^F-FET in inflammatory cells but increased uptake has been...
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