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Extracellular Recordings of Field Potentials from Single Cardiomyocytes
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ABSTRACT
Open microfluidic channels were used to separate the extracellular space around a cardiomyocyte into three compartments: the cell ends and a central partition (insulating gap). The microchannels were filled with buffer solution and overlaid with paraffin oil, thus forming the cavities for the cell ends. The central part of the cardiomyocyte rested on the partition between two adjacent microchannels and was entirely surrounded by the paraffin oil. This arrangement increased the...
Related newspaper, magazine, and journal articles from HighBeam Research
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Action Potential Duration Dispersion and Alternans in Simulated Heterogeneous Cardiac Tissue with a Structural Barrier
Biophysical Journal
; ABSTRACT Structural barriers to wave propagation in cardiac tissue are associated with a decreased threshold for repolarization alternans both experimentally and clinically. Using computer simulations, we investigated the effects of a structural barrier on the onset of spatially concordant and
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Seasonal Variation in Conduction Velocity of Action Potentials in Squid Giant Axons.
The Biological Bulletin
; FRANCISCO BEZANILLA Abstract. To determine whether the electrical properties of the squid giant axon are seasonally acclimated, action potentials, recorded at different temperatures, were compared between giant axons isolated from Loligo pealei caught in May, from relatively cold waters
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Calcium and cardiac arrhythmias: DADs, EADs, and alternans
Critical Reviews in Clinical Laboratory Sciences
; ABSTRACT: Rapid progress has been made in understanding the molecular mechanisms by which calcium ions mediate certain cardiac arrhythmias. Principal advances include imaging of cytosolic calcium in isolated cells and in intact tissues, use of fluorescent indicators and monophasic action potentials
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Deep brain stimulation and speech: a new model of speech function and dysfunction in Parkinson's disease.(Health Care Forum)
Journal of Medical Speech - Language Pathology
; Since its first description in 1980 (Cooper, Upton, & Amin, 1980), deep brain stimulation (DBS) has become a remarkably effective therapy for an expanding range of neurological and psychiatric disorders. It is standard accepted therapy for Parkinson's disease (PD) (Deep-Brain Stimulation for
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Imaging the heart: computer 3-dimensional anatomic models of the heart
Journal of Electrocardiology
; Abstract Since the 1960s, models of the action potential in various cardiac cell types have been developed, and since the 1990s, 3-dimensional anatomic (or geometric) models of various cardiac structures have been developed. We are approaching the time when, for one species, we should have a
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