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Microbiology and immunology
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During the past 25 years, significant advances have been made in our understanding of the immunology and microbiology of otitis media (OM). The report of the Sixth Research Conference on Recent Advances in Otitis Media,1 as well as an excellent and timely review called "Recent Developments in the Immunology of Otitis Media,"2 detail the basic framework of the microbiology and the immune system and its role in OM, and these will not be repeated here. It is the intent of this Report to review -...
Related newspaper, magazine, and journal articles from HighBeam Research
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Induction of mucous cell metaplasia by tumor necrosis factor alpha in rat middle ear: The pathological basis for mucin hyperproduction in mucoid otitis media
The Annals of Otology, Rhinology & Laryngology
; Mucoid otitis media (MOM), one of the leading causes of acquired hearing loss in children, is characterized by mucous cell hyperplasia in the middle ear cleft associated with mucin accumulation in the middle ear cavity. The factors that stimulate mucous cell metaplasia-hyperplasia and mucin
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Definitions, terminology, and classification of otitis media
The Annals of Otology, Rhinology & Laryngology
; INTRODUCTION We are indebted to the late Ben H. Senturia for organizing a small task force of clinicians and scientists to meet with him in St Louis in 1978 to reach a consensus on the definitions, terminology, and classification of otitis media. The report of the task force was published in the
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Role of tumor necrosis factor and interleukin-1 in endotoxin-induced middle ear effusions
The Annals of Otology, Rhinology & Laryngology
; In a rat model, we investigated the role of tumor necrosis factor (TNF) and interleukin-I (IL-1) in endotoxin-induced middle ear effusions (MEEs). After the eustachian tube was obstructed, the middle ear was transtympanically injected with 35 (mu)L of either 1 ) 1 mg/ mL lipopolysaccharide (LPS);
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Middle Ear Adenoma
Archives of Pathology & Laboratory Medicine
; Middle ear adenoma is a benign tumor of the middle ear that can have exocrine (mucinous) and/or neuroendocrine differentiation. Early authors described a separate tumor with predominantly neuroendocrine differentiation as a middle ear carcinoid tumor, but these are now known to be the same tumor.
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Effect of penicillin on formation of fibrous adhesions in acute otitis media
The Annals of Otology, Rhinology & Laryngology
; Fibrous middle ear adhesions are occasionally encountered in middle ear surgery and may cause a hearing impairment. Although usually associated with chronic otitis media, adhesions are also found following a single episode of experimental acute suppurative otitis media, suggesting a pathogenesis
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Managing otitis media with effusion in young children. (Otitis Media Guideline Panel)(includes bibliography)
American Family Physician
; Purpose and Scope Otitis media (inflammation of the middle ear) is the most frequent primary diagnosis in children younger than age 15 years. Otitis media particularly affects infants and preschool-age children: almost all children experience at least one episode of otitis media before age six
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Immunologic and histologic observations in reovirus-induced otitis media in the mouse
The Annals of Otology, Rhinology & Laryngology
; The goals of this study were to develop a mouse model for virally induced otitis media, and to study the immune response to infection. Intranasal inoculation of mice by reovirus was used to induce otitis media. Immunohistochemical evidence for the presence of reovirus in the nasopharynx, eustachian
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Course of IL-1(beta), IL-b, IL-8, and the TNF-(alpha) in the middle ear fluid of the guinea pig otitis media model induced by nonviable Haemophilus influenzae
The Annals of Otology, Rhinology & Laryngology
; To characterize the local response in acute otitis media, courses of interleukin (IL)-lIB, IL-6, IL-8, and tumor necrosis factor (TNF) a in middle ear fluid (MEF) of the guinea pig otitis media model induced by nonviable Haemophilus influenzae were investigated with enzyme-linked immunosorbent
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Middle ear gas composition in pathologic conditions: Mass spectrometry in otitis media with effusion and atelectasis
The Annals of Otology, Rhinology & Laryngology
; It is generally assumed that the gas enclosed in the middle ear and mastoid air cell system is subject to continuous absorption, and that partial pressures for oxygen and carbon dioxide equal those of "mixed venous blood." We previously determined the concentrations in 10 adults with healthy ears
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Treatment of otitis media.
American Family Physician
; TABLE 1 Common Causes of Otitis Media and Possible Predisposing Factors Biologic Adenoid hypertrophy Racial differences (e.g., extreme tube patency among Native American Indians) Male gender Family history Congenital anomalies (e.g., cleft palate) Size of middle ear structures Premature birth or
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