BK virus infection in kidney transplantation: a case for early intervention

Progress in Transplantation | June 1, 2006| | Copyright

The prognosis for renal allograft survival in a patient with BK virus-associated nephropathy is distressing because nearly 50% of affected grafts are lost. With these statistics in mind, attempting clinical intervention before BK virus disease develops seems appropriate. Noninvasive screening tools such as tests to detect decoy cells in urine can enable diagnosis of BK viral infection in its early stages. Although it is not entirely clear which patients with BK infection will have BK disease develop, it may be possible to intervene in this early warning period to prevent the further ...

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