Chemotaxis, viability, and labeling stability of leukocytes labeled with (99m)Tc-exametazime stabilized with methylene blue

From: The Journal of Nuclear Medicine | Date: March 1, 2001| Author: Roca, Manuel; Iglesias, Fernando; Garcia, Victor; Armero, Felix; Diaz, M Carmen | Copyright information

The in vitro viability, chemotaxis, and labeling stability of leukocytes labeled using ^sup 99m^Tc-exametazime stabilized with methylene blue were evaluated and compared with those obtained using nonstabilized ^sup 99m^Tc-exametazime. Methods: Two identical leukocyte populations, from 30 healthy donors, were labeled simultaneously using freshly prepared and 2-h-old stabilized ^sup 99m^Tc-exametazime. The following quality control techniques were performed on each labeled leukocyte sample: eos...

Related newspaper, magazine, and journal articles from HighBeam Research

Effects of methylene blue stabilizer on in vitro viability and chemotaxis of (99m)Tc-exametazime-labeled leukocytes
The Journal of Nuclear Medicine ; ... effects of methylene blue/phosphate ... stabilizer on the labeling efficiency ... integrity, chemotaxis, and in vitro stability of leukocytes labeled with ^sup 99,^Tc-exametazime. Methods ... nonstabilized or stabilized ^sup ...