Quantitative Trait Loci With Age-Specific Effects on Fecundity in Drosophila melanogaster

From: Genetics | Date: March 1, 2006| Author: | Copyright information

ABSTRACT

Life-history theory and evolutionary theories of aging assume the existence of alleles with age-specific effects on fitness. While various studies have documented age-related changes in the genetic contribution to variation in fitness components, we know very little about the unde rlying genetic architecture of such changes. We used a set of recombinant inbred lines to map and characterize the effects of quantitative trait loci (QTL) affecting fecundity of Drosophila melanogaster females at 1 and 4 weeks of age. We identified one QTL on the second chromosome and one or two QTL ...

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