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Reformulation provides IOP control more safely
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Fewer side effects
Brimonidine tartrate solution stabilized with Purite reduces likelihood of ocular allergy
Austin, TX-Brimonidine-Purite 0.15% (Alphagan P, Allergan), a new formulation of brimonidine tartrate ophthalmic solution in which benzalkonium chloride has been replaced with Purite, offers IOP-lowering efficacy comparable to brimonidine 0.2% (Alphagan) with the benefit of a superior safety profile, said Thomas R. Walters, MD.
Purite is a stabilized oxychloro complex and oxidative preservative found in some marketed ocular lubricant and saline solutions. It has bacteriocidal ...
Related newspaper, magazine, and trade journal articles from HighBeam Research
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IOP-lowering drug a versatile choice in large-scale study
; ...open-label study, mean IOP reductions from baseline were 7.5 mm Hg (29.7%) among previously...medication, and 4.2 mm Hg (18.6%) when bimatoprost...latanoprost, the mean IOP reductions at 1 and...by a mean of 5.1 mm Hg (21.3%) after 1 month and 5.6 ...
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Canaloplasty safely enhances aqueous outflow
; ...patients who were evaluated, mean IOP was 14.0 mm Hg (range, 0 to 40 mm Hg),and...of 59 patients showed that mean IOP was 16.5 mm Hg (range, 6 to 26 mm Hg). At...in 20 patients evaluated, mean IOP was 13.7 mm Hg ...
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Selective laser trabeculoplasty as effective as ALT
; ...600 mW per spot. Mean IOP at baseline was 23.6 mm Hg in both groups. Measurements...between treatments. Mean IOP decreased slightly at 1 week, to 21.3 mm Hg in the SLT eyes and...visits. At 6 months, mean IOP was 18.0 and 18.3 mm Hg in the ...
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Viscocanalostomy appears favorable for IOP control
; ...mean of 24.4 mm Hg preoperatively to 5.4 mm Hg on the first day after surgery. Mean IOP was 7 mm Hg at 7 days and 13.4 mm Hg at 1 month...thereafter. Mean IOP was decreased...reduction of mean IOP from 21.3 to 13 ...
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Material key to glaucoma drainage device
; ...AGV group (6.4 versus 10.8 mm Hg). By 1 month, mean IOP had risen in both groups...polypropylene S2 AGV (15.2 mm Hg). Mean IOP increased slightly further...in the FP7 group and 15.7 mm Hg in the S2 group. Mean IOP values in the FP7 group...
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Drainage device has fewer complications
; ...device. Preoperatively, the mean IOP was 29.6 mm Hg; it dropped to 11.2 mm Hg...year. By the third year, the mean IOP was 13 mm Hg and then by the end of the...1 year, 138 eyes showed a mean IOP drop of 8 mm Hg, from 24 to 16 ...
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Brimonidine 0.15% effective adjunctive therapy for open-angle glaucoma, ocular hypertension
; ...At 1 month, the mean IOP lowered to 16.1 mm Hg; at 2 months, the mean IOP was at 16.8 mm Hg. From the latanoprost-treat...and an additional mean IOP reduction of 5.1 mm Hg (23%) at 2 months...0.002), with a mean IOP of 18.6 ...
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Research finds SLT all-around tool for glaucoma management
; ...age from 34 to 94 years (mean, 69 years). Mean IOP among the 486 eyes was 20.6 mm Hg at baseline and decreased...age from 24 to 95 years (mean, 71 years). Mean IOP pre-SLT in that group was 21.8 mm Hg and it was decreased by 6.4 mm Hg (29%) ...
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IOP-lowering efficacy of bimatoprost, latanoprost weighed
; ...were not within 2 mm Hg of each other. Data...two-thirds). Baseline mean IOP was also comparable...values were 1.2 to 2.2 mm Hg greater in the bimatoprost...tanoprost eyes. Mean IOP values throughout...from 16.5 to 17.4 mm Hg in the ...
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Study results point to efficacy of once-daily bimatoprost
; ...m. (25.8 to 26.0 mm Hg), and not significantly...throughout the study, mean IOP was consistently...group. At 6 months, mean IOP at the four measurement...from 16.6 to 17.7 mm Hg with bimatoprost...two groups, with mean IOP values ranging from 17 to 18.7 ...
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