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GLUTATHIONE IN CANCER BIOLOGY AND THERAPY
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* The glulathione (GSH) content of cancer cells is particularly relevant in regulating mutagenic mechanisms, DNA synthesis, growth, and multidrug and radiation resistance. In malignant tumors, as compared with normal tissues, that resistance associates in most cases with higher GSH levels within these cancer cells. Thus, approaches to cancer treatment based on modulation of GSH should control possible growth-associated changes in GSH content and synthesis in these cells. Despite the potential...
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Executive Summary Report1
The Journal of Nutrition
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; ... helps protect against heart disease, cancer and many other diseases, according ... damage that can cause heart disease, cancer, aging and about 80 other diseases ... Packer, Ph.D., et al. in Free Radical Biology and Medicine in 1995. This therapy has been effective in treating children ... a previous ...
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Molecular methodologies in nutrition research
The Journal of Nutrition
; ... Research1 Steven D. Clarke and Sooja K. Kim2 Nutritional Sciences and the Institute for Molecular and Cellular Biology, The University of Texas, Austin, TX 78712 In the early stages of the evolution of life forms, cellular ... beneficial and detrimental in the etiology of such nutritionally related pathophysiologies as ...
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