Effects of Short-Term Glucagon Administration on Gluconeogenic Enzymes in the Liver of Midlactation Dairy Cows1

Journal of Dairy Science | February 1, 2006| | Copyright

ABSTRACT

During lactation, the dairy cow experiences an increased demand for glucose to support milk production. Increased glucose demand can be met through increased capacity for gluconeogenesis, increased supply of glucose precursors, or a combination of both processes. Glucagon, a key hormone in glucose homeostasis, acts to promote gluconeogenesis and increase glucose output from liver. The objective of this study was to determine the effect of short-term administration of glucagon on expression of gluconeogenic enzymes in lactating dairy cattle. Sixteen multiparous Holstein cows were ...

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