Colon cancer mutation traced to 1630

From: Deseret News (Salt Lake City) | Date: January 2, 2008| Author: Lois M. Collins Deseret Morning News | Copyright information

Utah cancer researchers have traced a hereditary form of colon cancer back to a married couple who arrived in America from England around 1630.

Using two large families -- one in Utah and another in New York - - that carry an identical gene mutation that increases risk of colorectal cancer, the Huntsman Cancer Institute-led team followed the genealogy back to discover what they call a "founder mutation," which is one shared by a common ancestor and believed to have begun with that indi...

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