'Master' gene that alters tumours

From: New Straits Times | Date: March 23, 2008 | Copyright information

New Straits Times
03-23-2008
'Master' gene that alters tumours
Edition: New Sunday Times
Section: Main Section

GENETICISTS have identified a super gene which causes breast cancer to metastasise, the process by which the disease spreads to other organs.

Described as a "master regulator", the SATB1 gene alters the behaviour of at least 1,000 other genes within tumour cells.
When over-activated, the gene makes cancer cells proliferate, and when neutralised, it stops the cells from dividing and migrating.

The findings could not only pave the way to diagnostic tools that show the likelihood of ...

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