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Analysis: Successful use of gene therapy to restore hearing in a deaf mammal, guinea pigs
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JENNIFER LUDDEN
Weekend Edition - Sunday (NPR)
02-13-2005
Analysis: Successful use of gene therapy to restore hearing in a deaf mammal, guinea pigs
Host: JENNIFER LUDDEN
Time: 8:00-9:00 PM
JENNIFER LUDDEN, host:
From NPR News, this is ALL THINGS CONSIDERED. I'm Jennifer Ludden.
For the first time scientists have successfully used gene therapy to restore hearing in a deaf mammal: guinea pigs. It's not yet clear how well the animals hear following the treatment, but it does suggest that using a similar approach to treat deafness in humans is possible. We begin our coverage of this ...
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Guinea pigs can regenerate key cells for hearing
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; ...researchers made adult guinea pigs grow new sound-sensing cells, called hair cells, in the spiral...long the newborn hair cells can survive or...hearing to deaf guinea pigs. For the reported...initial supply of hair cells. In a surgical...cochleas of adult ...
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Hearing repaired: gene therapy restores guinea pigs' hearing.(This Week)
Magazine article from: Science News
; ...says. Like people, guinea pigs use auditory hair cells, found deep inside...succeeded in regrowing hair cells in adult guinea pigs (SN: 6/7/03, p. 355...researchers reexamined the guinea pigs for signs of new hair cells and hearing. Animals...
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Analysis: Successful use of gene therapy to restore hearing in a deaf mammal, guinea pigs
Transcript from: NPR Weekend Edition - Sunday
; ...a deaf mammal, guinea pigs Host: JENNIFER...a deaf mammal: guinea pigs. It's not yet clear...therapy to give guinea pigs a gene called Atoh...them to make new hair cells. The cells didn...destroyed their hair cells and made the animals...You can't ask ...
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An earful of hair cells. (Eureka: emerging technologies).(gene therapy)(Brief Article)
Magazine article from: R & D
; ...employed gene therapy to grow new auditory hair cells in mature guinea pigs. This was achieved by introducing a...were able to produce novel sensory hair cells. This could lead to innovative treatments...which results from damaged or destroyed hair cells. More info: ...
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Outer hair cells: The inside story
Magazine article from: The Annals of Otology, Rhinology & Laryngology
; The neurobiology of hair cells is reviewed, including their transduction apparatus, the...potentials, and the similarities and differences between inner hair cells and outer hair cells (OHCs). Intracellular recordings from hair cells in vivo...
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Good vibrations. (hair cells hold the secret of hearing)(includes related articles on the pinna and insects that can hear bat ultrasound) (Cover Story)
Magazine article from: Discover
; ...sacrificing. Those hearing receptors are called hair cells, specialized sensory cells that are among...princesses turning straw into gold, the inner hair cells transform the mechanical forces of sound...ocean to the shore to dry land. Yet the hair cells at its core have hardly been ...
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Unwanted guinea pigs have guardian angels
Newspaper article from: Oakland Tribune
; ...apartment, but left 15 frightened and sick guinea pigs behind. She feared they would be euthanized...took them in. DuHamel already had 10 guinea pigs awaiting adoption at her house, but...new ones back to health. Cages full of guinea pigs are now stacked on every available surface...
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Deaf chickens hear again. (regeneration of hair cells in inner ear)
Magazine article from: Science News
; ...because they believed the inner ear's hair cells, which convert sound into electrical...certain fish and amphibians could produce hair cells throughout life. Now Corwin and Douglas...from the chicks' ears and found that hair cells were missing. Over the next 10 days...
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Hair Cells micromechanics and Hearing
Magazine article from: The Annals of Otology, Rhinology & Laryngology
; ...the latest information and thinking on hair cells and their auditory function. This is...present material on "self-repair" of hair cells, fast adaptation as a mechanical tuning mechanism, sea anemone versus vertebrate hair cells, gene regulation of hair cell differentiation...
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New inner ear hair cells grow in rat tissue.(Brief Article)
Magazine article from: Science News
; ...snail-shaped organ of the inner ear whose tiny hair cells detect sound vibrations. The cochlea...nerves carry to the brain. Once destroyed, hair cells don't regenerate. Researchers at Genentech...Francisco now report that they've grown new hair cells in tissue taken from newborn ...
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