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thalidomide
thalidomide
The Oxford Pocket Dictionary of Current English
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2009
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© The Oxford Pocket Dictionary of Current English 2009, originally published by Oxford University Press 2009. (Hide copyright information)
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tha·lid·o·mide
/ [unvoicedth]əˈlidəˌmīd/
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n.
a drug formerly used as a sedative, but withdrawn in the early 1960s after it was found to cause congenital malformation or absence of limbs in children whose mothers took the drug during early pregnancy.
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Thalidomide: Important Patient Information.(Pamphlet)
Newspaper article from: Pamphlet by: Food and Drug Administration; 9/11/1997; 700+ words
; ...one dose can cause severe birth defects. Thalidomide (tha-lid-o-mide) was first marketed...during pregnancy. At that time no one knew thalidomide caused birth defects. Thalidomide is not approved for general sale in the United...
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Thalidomide resurfaces with FDA ruling
Magazine article from: Dermatology Times; 9/1/1999; ; 700+ words
; ...California School of Medicine, discusses thalidomide and its uses for dermatologic diseases...Q Why is there a sudden interest in thalidomide? The primary reason is the recent approval of thalidomide by the FDA for the treatment of erythema...
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Thalidomide Can Put the Brakes on Multiple Myeloma.
Magazine article from: Family Practice News; 2/1/2000; ; 700+ words
; ...still in remission at 13 months. "Thalidomide is the first agent of note for multiple...multiple myeloma has a new member: thalidomide. Results of several preliminary studies...at the meeting provide evidence that thalidomide (Thalomid) has dramatic activity in...
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Thalidomide Pharmion application to be resubmitted to EMEA for multiple myeloma.
Newspaper article from: Biotech Business Week; 6/28/2004; 700+ words
; ...Evaluation Agency (EMEA) for the use of Thalidomide Pharmion 50 mg to treat patients with...patient and compassionate use sales of thalidomide, provided by the company on May 3...application with the EMEA for the use of thalidomide in the treatment of cutaneous manifestations...
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 "Weekend Edition - Saturday (NPR)")
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Thalidomide Use By AIDS, Cancer Patients a Controversy
Transcript from: Weekend Edition - Saturday (NPR); 9/30/1995; 700+ words
; 00-00-0000 In the early '60s, thalidomide's use by pregnant women caused tragic deformations...after pregnant women were given the drug thalidomide to relieve morning sickness. Thalidomide was subsequently banned worldwide. Now scientists...
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THALIDOMIDE TO MYELOMA THERAPIES CAN ENHANCE CLINICAL ACTIVITY.
News Wire article from: AsiaPulse News; 12/13/2006; 700+ words
; ...Meeting demonstrate the following: * Thalidomide plus dexamethasone yield superior response...Maintenance therapy combining low-dose thalidomide plus prednisolone following transplant...new data presented from two studies of thalidomide in combination therapy, including updated...
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Thalidomide Receives Australian Recommendation for Approval For the Treatment of Relapsed and Refractory Multiple Myeloma; Thalidomide also received an approval recommendation for Acute Manifestations of Inflammatory Complications of Leprosy.
PR Newswire; 8/19/2003; 700+ words
; ...recommended for approval Pharmion's thalidomide for the treatment of both patients with...represent the first approval worldwide for thalidomide as a therapy for relapsed and refractory...Food and Drug Administration approved thalidomide for the treatment of cutaneous manifestations...
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Thalidomide returns, as do fears
Newspaper article from: The Boston Globe; 9/14/1997; ; 700+ words
; ...middle-aged and older, the word "thalidomide" still conjures up tragic images of...Drug Administration, today retells the thalidomide story with the dispassion of a scientist...83, says she still worries about thalidomide -- she calls it a "fascinating but...
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Thalidomide: Tragic Past and Promising Future
Magazine article from: Mayo Clinic Proceedings; 7/1/2004; ; 700+ words
; Thalidomide ([alpha]-N-[phthalimido] glutarimide...the market as a sedative.1,3,4 Thalidomide lacked the typical addictive properties...was practically impossible. Thus, thalidomide was believed to be basically nontoxic...
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Thalidomide Therapy and Deep Venous Thrombosis in Multiple Myeloma
Magazine article from: Mayo Clinic Proceedings; 12/1/2005; ; 700+ words
; ...with the arrival of active agents such as thalidomide and bortezomib.1-4 Thalidomide, once discarded because of its teratogenicity...disease.5-8 In fact, the combination of thalidomide plus dexamethasone (Thal/Dex) has rapidly...
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Thalidomide
Encyclopedia entry from: Gale Encyclopedia of Cancer
Thalidomide Definition Thalidomide, which is also known as Thalomid, is a drug used to fight aggressive...studies, either in progress or recently completed, that suggest thalidomide can slow or stop the spread of cancer of the brain, breast...
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Thalidomide: Global Tragedy
Book article from: American Decades
THALIDOMIDE: GLOBAL TRAGEDY Unexpected Benefits Thalidomide was developed in the United States as a possible antiseizure...that continued testing. Chemie Gruenenthal found that thalidomide was a reasonably effective sedative with an unusual...
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thalidomide
Book article from: The Oxford Companion to the Body
thalidomide and the thalidomide disaster are firmly riveted together in the minds of the population...occurence might be repeated with another new and promising drug. Thalidomide was introduced around 1957 as a safe hypnotic and sedative . In...
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Kelsey, Frances Kathleen Oldham
Book article from: Chemistry: Foundations and Applications
...first drug she was asked to evaluate was thalidomide, a sedative prescribed to pregnant...chemist who assisted her in the review of thalidomide were immediately concerned that the...reports that some patients who had taken thalidomide had developed peripheral neuritis...
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Kelsey, Dr. Frances Oldham 1914-
Book article from: American Decades
...denying approval for the distribution of thalidomide in the United States. She did so in...the American rights to a drug called thalidomide that had been marketed under various...existing evidence for the side effects of thalidomide was inconclusive, it exerted extensive...
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