Dwingeloo Radio Observatory
Dwingeloo Radio Observatory A radio observatory at Dwingeloo, about 60 km southwest of Groningen, in the Netherlands, owned and operated by the Netherlands Foundation for Research in Astronomy. It contains a single 25-m dish, opened in 1956.
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L-DOPA with CGS 21680 may open new therapeutic avenues for Parkinson disease.
Newspaper article from: Biotech Week; 12/8/2004; 700+ words
; ...The neuroprotective effect of L-DOPA co-administered with the adenosine...improvement by potentiating the effects of (L)-DOPA as well as a decrease in secondary effects such as (L)-DOPA-induced dyskinesia. "(L)-DOPA...
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A Technique for Standardized Central Analysis of 6-^sup 18^F-Fluoro-L-DOPA PET Data from a Multicenter Study
Magazine article from: The Journal of Nuclear Medicine; 7/1/2004; ; 700+ words
; ...a large 6-^sup 18^F-fluoro-L-DOPA (^sup 18^F-DOPA) PET study comparing...the dopamine agonist ropinirole or L-DOPA. This trial involved a "distributed...randomized (1:1) to ropinirole or L-DOPA therapy, and ^sup 18^F-DOPA PET...
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The Effects of Carbidopa on Uptake of 6-^sup 18^F-Fluoro-L-DOPA in PET of Pheochromocytoma and Extraadrenal Abdominal Paraganglioma
Magazine article from: The Journal of Nuclear Medicine; 10/1/2007; ; 700+ words
; ...sup 18^F-fluoro-L-3,4-dihydroxyphenylalanine (^sup 18^F-DOPA) PET is a useful tool...Key Words: 6-fluoro-DOPA; 6-^sup 18^F-fluorodopamine...sup 18^F-fluoro-L-3,4-dihydroxyphenylalanine (^sup 18^F-DOPA) PET has emerged as a...
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Quantification of L-dopa and dopamine in squid ink: implications for chemoreception.
Magazine article from: The Biological Bulletin; 8/1/1994; ; 700+ words
; ...that squid olfactory organs detect L-dopa, a key chemical in melanogenesis...fluorometrically. Standard curves constructed for L-dopa and dopamine allowed quantitation from individual ink sacs. We found that L-dopa was present in undiluted ink at a mean...
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Effects of chronic L-DOPA treatment elucidated.
Newspaper article from: Proteomics Weekly; 11/29/2004; 700+ words
; ...net) -- The effects of chronic L-DOPA treatment on basal ganglia glutamate...3,4-dihydroxyphenylalanine (L-DOPA)," scientists in France explained...with or without subsequent chronic L-DOPA treatment on several parameters of...
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Fluorine-18-fluoro-L-DOPA dosimetry with carbidopa pretreatment
Magazine article from: The Journal of Nuclear Medicine; 11/1/1998; ; 700+ words
; ...18^F]-6-fluoro-L-3,4dihydroxy-phenylalanine (^sup 18^F-DOPA, fluoro-DOPA) dates...adjunct to ^sup 18^F-DOPA PET imaging (3-6...blocks peripheral aromatic L-amino acid decarboxylase...decarboxylation of ^sup 18^F-DOPA to ^sup 18^Fdopamine...
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Involvement of the Basal Ganglia in Refractory Epilepsy: An ^sup 18^F-Fluoro-L-DOPA PET Study Using 2 Methods of Analysis
Magazine article from: The Journal of Nuclear Medicine; 3/1/2005; ; 700+ words
; ...fluorodihydroxyphenylalanine (^sup 18^F-fluoro-L-DOPA) has recently demonstrated a reduction...analysis of the ^sup 18^F-fluoro-L-DOPA uptake constant (K^sub i^, min...decrease of ^sup 18^F-fluoro-L-DOPA uptake was observed in the 3 groups...
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Variability in spatiotemporal gait characteristics over the course of the L-dopa cycle in people with advanced Parkinson disease.
Magazine article from: Physical Therapy; 10/1/1998; ; 700+ words
; ...levorotary dihydroxy phenylalinine (L-dopa), the precursor of dopamine, is given. The L-dopa cycle is the interval between 2 consecutive...have a stable clinical response to L-dopa therapy, with reduction in tremor...
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Time profile of L-dopa metabolites in nonhuman primates determined.
Newspaper article from: Drug Week; 1/16/2004; 700+ words
; ...superscript]18F]6-fluoro-L-dopa metabolites in nonhuman primates in...superscript]18F] 6-fluoro-L-DOPA (FDOPA), may have multiple turnover...superscript]18F] 6-fluoro-3-methyl- L-DOPA (3-OMFD), FDA, [[superscript...
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Characterization of Hyperinsulinism in Infancy Assessed with PET and ^sup 18^F-Fluoro-L-DOPA
Magazine article from: The Journal of Nuclear Medicine; 4/1/2005; ; 700+ words
; ...dihydroxyphenylalanine (^sup 18^F-fluoro-L-DOPA) and (b) to distinguish between...injection of ^sup 18^F-fluoro-L-DOPA (4.0 MBq/kg weight). Four or...pancreatic uptake of ^sup 18^F-fluoro-L-DOPA was observed in 5 patients, whereas...
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l-dopa
Book article from: The Columbia Encyclopedia, Sixth Edition
l-dopa , drug used to alleviate some of the symptoms...blood. A metabolic precursor of dopamine, l-dopa does enter the brain via the bloodstream...Furthermore, virtually all patients on l-dopa experience side effects including nausea...
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L-dopa
Book article from: A Dictionary of Biology
L-dopa See dopa .
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dopa
Book article from: A Dictionary of Biology
dopa ( dihydroxyphenylalanine ) A derivative of the amino acid tyrosine. It is...synthesis of dopamine , noradrenaline , and adrenaline . The laevorotatory form, L-dopa ( levodopa ), is administered in the treatment of Parkinson's disease...
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Dopamine Receptor Agonists
Encyclopedia entry from: Gale Encyclopedia of Neurological Disorders
...Dopaminergic agonist drugs such as levodopa (L-dopa) along with carbidopa, bromocriptine...alone or in combinations. Description L-dopa (levodopa) is a precursor of dopamine...enhanced because carbidopa increases L-dopa transport to the brain and decreases...
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Dopamine
Book article from: Chemistry: Foundations and Applications
...compound L-dihydroxyphenylalanine (L-dopa) via the enzyme dopa decarboxylase...administering the precursor of dopamine, L-dopa. In order to prevent concentrations...norepinephrine from increasing as well, L-dopa is given in conjunction with a drug...
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