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ligand
ligand
ligand 1. An atom,
ion, or molecule that acts as the electron-donor partner in one or more co-ordination bonds. A
heterocyclic ring is formed if the ligand is an organic compound, and the product is termed a chelate.
2. A molecule (e.g. an antibody) that can bind to specific sites on
cell membranes.
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Ligand Pharmaceuticals and the SALK Institute Enter Settlement Agreement and Mutual Release of All Claims.
Business Wire; 9/5/2008; 700+ words
; SAN DIEGO -- Ligand Pharmaceuticals Incorporated (NASDAQ...ongoing arbitration between the parties. Ligand and SALK agreed to terminate their January...conveyance of rights to any third party. Ligand does not believe that it requires a license...
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Ligand and Private Investors Complete Second Investment in X-Ceptor.
Business Wire; 10/7/1999; 700+ words
; ...BW HealthWire)--Oct. 7, 1999-- Ligand Pharmaceuticals Incorporated (Nasdaq...the field of orphan nuclear receptors. Ligand invested $3.2 million in cash and other...25 million. At the second closing, Ligand also issued to X-Ceptor investors...
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LIGAND ELECTS TO RECEIVE MILESTONE PAYMENTS FROM PFIZER IN LIGAND COMMON STOCK; LIGAND COULD RETIRE OVER 101,000 SHARES
PR Newswire; 5/7/1996; 700+ words
; SAN DIEGO, May 7 /PRNewswire/ -- Ligand Pharmaceuticals Inc. (Nasdaq: LGND...from Pfizer Inc (NYSE: PFE) paid in Ligand stock, currently held by Pfizer. Under the terms of a recently settled lawsuit, Ligand has been deemed to have earned a second...
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Ligand Pays Elan Milestone for Morphelan--TM-- NDA Submission.
Business Wire; 6/8/2000; 700+ words
; ...BW HealthWire)--June 8, 2000 Ligand Pharmaceuticals Incorporated (Nasdaq...plc (NYSE:ELN) 367,183 shares of Ligand common stock in connection with Elan...10.89, the average closing price of Ligand common stock for the five trading days...
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Ligand Exercises First Option to Buy Down ONTAK Royalties.
Business Wire; 1/7/2005; 700+ words
; SAN DIEGO -- Ligand Pharmaceuticals (NASDAQ:LGND) announced...royalties payable to Lilly on sales of Ligand's marketed cancer drug ONTAK(R) (denileukin diftitox) in the United States. Ligand recorded sales of $34.3 million for...
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Ligand Exercises Final Option to Buy Down ONTAK Royalties.
Business Wire; 4/7/2005; 700+ words
; SAN DIEGO -- Ligand Pharmaceuticals Incorporated (NASDAQ...royalties payable to Lilly on sales of Ligand's marketed cancer drug ONTAK(R) (denileukin diftitox) in the United States. Ligand will make a one-time cash payment of...
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Ligand Restructures AVINZA License and Supply Agreement.
Business Wire; 11/12/2002; 700+ words
; ...Exchange for $100 Million Up-Front Payment Ligand to Purchase and Retire 2.2 Million Ligand Shares Held by Elan; Elan Agrees to 6-Month Lock-Up on 11.8 Million Remaining Shares Ligand Pharmaceuticals (Nasdaq: LGND) announced...
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Ligand Terminates Long-Term Lease Obligation.
Business Wire; 8/10/2009; 700+ words
; ...Long-term Overhead Costs SAN DIEGO -- Ligand Pharmaceuticals Incorporated (NASDAQ...Diego. Under the terms of the agreement, Ligand will pay a termination fee of $14.3...million in April 2011. In addition, Ligand entered into a new lease for a period...
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Ligand Issues $40.0 Million Zero Coupon Convertible Notes to Elan Corporation, plc.
Business Wire; 7/16/1999; 700+ words
; ...BW HealthWire)--July 15, 1999-- Ligand Pharmaceuticals Incorporated (Nasdaq...Agreement). The Notes are convertible into Ligand common stock at $14.00 per share...11.00. Under the Elan Agreement, Ligand may use the proceeds of the Note issuance...
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Ligand and Elan Launch Strategic Alliance; Provides Ligand With Up To $130 Million in Funding, Rights to Morphelan for HIV and Oncology Markets.
Business Wire; 11/10/1998; 700+ words
; ...BW HealthWire)--Nov. 9, 1998--Ligand Pharmaceuticals Incorporated (Nasdaq:LGND...which Elan agreed to purchase $20 million of Ligand Common Stock and to purchase from Ligand up to $110 million in issue price of Zero Coupon...
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Ligand Pharmaceuticals Incorporated
Book article from: International Directory of Company Histories
Ligand Pharmaceuticals Incorporated 10275 Science...Operating out of San Diego, California, Ligand Pharmaceuticals Incorporated discovers...cardiovascular diseases, and inflammatory diseases. Ligand ’ s drug development program relies...
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Ligand
Encyclopedia entry from: The Gale Encyclopedia of Science
Ligand In inorganic chemistry, ligands are molecules...are bonded to metal atoms or ions. The ligand changes the metal ’ s ability...with it (Figure 1). Thus, the metal and ligand are joined by a covalent bond, consisting...
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ligand-gated ion channel
Book article from: A Dictionary of Biology
ligand-gated ion channel A type of ion channel that opens when a signal molecule (ligand) binds to an extracellular receptor region of...of the muscle cell membrane. Other types of ligand-gated ion channels are found at synapses and...
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ligand
Book article from: A Dictionary of Zoology
ligand An atom, ion, or molecule that acts as the electron-donor partner in one or more co-ordination bonds. A hetero-cyclic ring is formed if the ligand is an organic compound, and the product is termed a chelate.
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Coordination Compound
Encyclopedia entry from: The Gale Encyclopedia of Science
...are shared between transition metal and ligand. But in a coordination compound, both electrons come from a pair found on the ligand (Figure 1). Table 1. Typical Transition...Typical Ligands, L Name as Ligand Ordinary name Electrically :NH ammine...
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