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colchicine
colchicine
colchicine An alkaloid drug that is obtained from meadow saffron (see
COLCHICUM). It has a disruptive effect on microtubular activity (see
MICROTUBULE), though not on that of
microfilaments. Thus, it affects tissue metabolism generally and
mitosis in particular. It can be used to induce
polyploidy in plants, because it prevents the development of the
spindle and so blocks the separation of
chromosomes during
mitosis.
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Colchicine for dermatologic diseases.
Magazine article from: Journal of Drugs in Dermatology; 3/1/2005; ; 700+ words
; ...authors review all aspects related to colchicine from its pharmacology to its usage in...diseases. ********** Introduction Colchicine has been prescribed in dermatology for...usage in several skin diseases. History Colchicine is an alkaloid extracted from the seeds...
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Colchicine for Acute Pericarditis.
Magazine article from: Clinical Cardiology Alert; 12/1/2005; 700+ words
; Colchicine for Acute Pericarditis Abstract &...Clinical Cardiology Alert. Synopsis: Colchicine added to conventional therapy for acute...increased it. Source: Imazio M, et al. Colchicine in Addition to Conventional Therapy...
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Ciclosporin/colchicine interaction: Colchicine toxicity: case report
Magazine article from: Reactions Weekly; 1/3/2009; ; 672 words
; ...ciclosporin immunosuppression, developed colchicine-induced toxicity after starting colchicine for suspected gout. The man, who had undergone...stated]. Three days later, he started colchicine 1 mg/day and, within 3 days, he developed...
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Ginkgo and Colchicine: Curiouser and Curiouser, says Alice. (Phytotherapy Review).(colchicine in placental blood)
Magazine article from: Townsend Letter for Doctors and Patients; 4/1/2002; ; 700+ words
; ...compound present which they identified as colchicine. (1) Naturally the scientists were...pregnant women. Only five of these contained colchicine and the group reported that all of the colchicine-containing blood samples came from women...
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FDA Approves Colcrys(TM) (colchicine, USP) for Prevention of Gout Flares.
PR Newswire; 10/19/2009; 700+ words
; New Colchicine Formulation Significantly Reduces Side...FDA) has approved Colcrys(TM) (colchicine, USP) for the prophylaxis (prevention...Colcrys is an oral, branded form of colchicine that has been formulated for optimal...
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Low-dose colchicine effective for acute gout.(RHEUMATOLOY)
Magazine article from: Internal Medicine News; 1/15/2009; ; 700+ words
; SAN FRANCISCO -- Low-dose colchicine appeared to be as effective as...5 mg t.i.d.) when using colchicine to treat gout flare, a recommendation...patients to receive high-dose colchicine, low-dose colchicine, or placebo...
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Does the photochemical conversion of colchicine into lumicolchicines involve triplet transients? A solvent dependence study
Magazine article from: Photochemistry and Photobiology; 3/1/2001; ; 700+ words
; ...Does the Photochemical Conversion of Colchicine into Lumicolchicines Involve Triplet...cycloisomerization of the tropolone ring of colchicine (COL) alkaloids. The mechanism of...and organ distribution of cationized colchicine-specific IgG and Fab fragments in...
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The 2009 Comprehensive Research Report on the Colchicine (CAS 64-86-8) Market.
M2 Presswire; 9/11/2009; 602 words
; ...Comprehensive Research Report on the Colchicine (CAS 64-86-8) Market(C)1994...researchandmarkets.com/research/63b370/colchicine_cas_64) has announced the addition of the "Colchicine (CAS 64-86-8) Market Research...
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Herbal Science Group Debunks Research Suggesting Presence of Toxin Colchicine in Ginkgo.
PR Newswire; 8/30/2001; 700+ words
; ...Testing Show that Suspected Toxic Chemical Colchicine is Not Found in Ginkgo Scientists say...Research that incorrectly suggests that colchicine has been detected in a ginkgo dietary...of accumulating the natural chemical colchicine (see below) in their placentas, thereby...
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Deaths from intravenous colchicine resulting from a compounding pharmacy error--Oregon and Washington, 2007.(Case study)
Newspaper article from: Morbidity and Mortality Weekly Report; 10/12/2007; ; 700+ words
; Colchicine for injection has been available in...providers but is not an accepted practice. Colchicine has well-known toxicities that limit...Washington and Oregon died after receiving IV colchicine for back pain from an alternative medicine...
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colchicine
Book article from: The Columbia Encyclopedia, Sixth Edition
colchicine , alkaloid extracted from plants of...saffron ). The metabolic effect of colchicine is not known, but it is thought that...it useful in the treatment of gout. Colchicine and derivatives such as demecolcine...
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Gout Drugs
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...inflammatory drugs, corticosteroids, or colchicine. Patients may also be advised to change...of drugs are used in treating gout. Colchicine helps relieve the symptoms of gout by...does not seem to be working t first. Colchicine may be taken regularly in low doses...
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Anti-Hyperuricemic Drugs
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...inflammatory drugs (such as indomethacin), colchicine, and corticosteroids. Colchicine causes side effects in a large number of individuals...of gout. Patients may also be treated with colchicine or non-steroidal anti-inflammatory drugs...
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colchicum
Book article from: World Encyclopedia
...white, or purple crocus-like flowers in bloom during the autumn. The corm contains colchicine, an alkaloid used to treat rheumatism and gout. Colchicine's ability to inhibit mitosis make it a valuable immunosuppressive drug and aid to cancer...
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Polyploidy
Book article from: Genetics
...in Plants Polyploidy can be induced with chemicals such as colchicine, as O. J. Eigsti first demonstrated in 1935. His work...but artificial ones are induced by mitotic poisons, like colchicine, that prevent spindle fiber formation. If one species has...
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