selective (o)estrogen receptor modulator

selective (o)estrogen receptor modulator (SERM) (si-lek-tiv) n. a drug that has oestrogen-like activity in some tissues and an anti-oestrogenic effect in others, depending on the manner of its binding with the oestrogen receptors. SERMs include tamoxifen, used in the treatment of breast cancer for its activity as an anti-oestrogen; and raloxifene, used in the treatment of osteoporosis for its oestrogenic effects on bone density.

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