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neomycin
neomycin
neomycin (nee-oh-my-sin) n. an aminoglycoside antibiotic used to treat infections caused by a wide range of bacteria, mainly those affecting the skin, ears, and eyes. It is usually applied in creams, ointments, or drops with other antibiotics, but can be given by mouth to sterilize the bowel before surgery.
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Single-laboratory validation for the quantification of neomycin B and neomycin C in animal feeds by liquid chromatography fluorescence detection with post-column derivatization.(SPECIAL SECTION ON FEED ADDITIVES AND CONTAMINANTS)(Report)
Magazine article from: Journal of AOAC International; 1/1/2009; ; 700+ words
; Neomycin is approved for feeds that treat and control...between 500-77 g/kg (227-35 g/lb) neomycin base; type B medicated feeds contain a maximum concentration of 154 g/kg neomycin base; and type C medicated feeds contain between...
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Ryanodine-induced structural alterations in the RyR channel suggested by neomycin block
Magazine article from: Biophysical Journal; 4/1/2002; ; 700+ words
; ...1963, 2002) we have reported that neomycin is a potent partial blocker of single...cardiac SR calcium release channels. Neomycin is unusual in that it is capable of blocking...study we have investigated the actions of neomycin on ion handling in the ryanodine-modified...
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Block of the ryanodine receptor channel by neomycin is relieved at high holding potentials
Magazine article from: Biophysical Journal; 4/1/2002; ; 700+ words
; ...actions of the aminoglycoside antibiotic neomycin on K^sup+^ conductance in the purified...calcium-release channel (RyR). Neomycin induces a concentrationand voltage...luminal block are markedly different. Neomycin has a greater affinity for the luminal...
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Electrostatic Mechanisms Underlie Neomycin Block of the Cardiac Ryanodine Receptor Channel (RyR2)
Magazine article from: Biophysical Journal; 12/1/2004; ; 700+ words
; ABSTRACT Neomycin is a large, positively charged, aminoglycoside...an electrostatic interaction between neomycin and putative regions of negative charge...concentration in single-channel experiments. Neomycin block is apparent at both cytosolic and...
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Declining susceptibility to neomycin and polymyxin B of pathogens recovered in otitis externa clinical trials.(Original Article)
Magazine article from: Southern Medical Journal; 5/1/2004; ; 700+ words
; ...usually treated empirically with topical neomycin/polymyxin B/hydrocortisone. The...conducted between 1995 and 1996, compared neomycin/polymyxin B/hydrocortisone with ofloxacin...isolates (including P aeruginosa) for neomycin and polymyxin B increased markedly in...
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Neomycin inhibits activation of cyclin D1; is antiproliferative to glioma cells.
Newspaper article from: Drug Week; 1/2/2004; 684 words
; ...NewsRx.com & NewsRx.net) -- Neomycin inhibits activation of cyclin D1; is...subscript]1 phase and assess the effects of neomycin on cyclin D1 protein detection by immunocytochemical...after 3 h of incubation of the cells with neomycin," wrote P. Cuevas and colleagues...
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Neomycin cripples the invasive capacity of glioma.
Newspaper article from: Angiogenesis Weekly; 6/20/2003; 589 words
; ...NewsRx.com & NewsRx.net) -- Neomycin cripples the invasive capacity of glioma...Our study investigated the role of neomycin on NF-kB activity in glioma cell cultures...NF-kBp65, which results show that neomycin decreases significantly the activation...
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In vitro study shows that neomycin inhibits glioma cell migration.
Newspaper article from: Obesity, Fitness & Wellness Week; 7/17/2004; 654 words
; ...NewsRx.com & NewsRx.net) -- Neomycin may play a role in the development of...Previous studies have indicated that neomycin inhibits glioma cells proliferation...investigating the antimigratory effect of neomycin," wrote P. Cuevas and colleagues...
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Severe generalised hypersensitivity reaction to topical neomycin after cataract surgery: a case report.(Case report)
Magazine article from: Journal of Medical Case Reports; 2/23/2008; ; 700+ words
; ...the form of urticaria and angioedema Neomycin is an antibiotic that is often used in the form of Maxitrol (Neomycin, Polymyxin B and Dexamethasone) after...allergic contact reactions to topical neomycin as 1 to 29/100,000 [7]. We describe...
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Turkeys added to neomycin label. (FDA Notice).
Magazine article from: Feedstuffs; 1/13/2003; 700+ words
; ...which provides for use of Neo-Sol 50 (neomycin sulfate) soluble powder for making medicated...caused by Escherichia coli susceptible to neomycin. The new supplemental ANADA provides for use of neomycin in the drinking water of growing turkeys...
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neomycin
Book article from: The Columbia Encyclopedia, Sixth Edition
neomycin , broad spectrum antibiotic effective...species of Proteus and Staphylococcus. Neomycin is mainly used topically in the treatment...used systemically, it is highly toxic. Neomycin was first isolated in 1949 by the American...
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Transgenic Animals
Book article from: Genetics
...The two most common selectable genes used in gene targeting are the neomycin resistance (neo r) gene, which allows cells to survive in the presence of the antibiotic neomycin, G418, and the thymidine kinase (TK ) gene from the herpes virus...
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Antibiotics, Topical
Encyclopedia entry from: Gale Encyclopedia of Surgery: A Guide for Patients and Caregivers
...in many forms, including creams, ointments, powders, and sprays. Some widely used topical antibiotics are bacitracin, neomycin, mupirocin, and polymyxin B. Among the products that contain one or more of these ingredients are Bactroban (a prescription...
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Colostomy
Encyclopedia entry from: Gale Encyclopedia of Surgery: A Guide for Patients and Caregivers
...enemas and/or oral preparations (GoLytely or Colyte) may be ordered to empty the bowel of stool. Oral anti-infectives (neomycin, erythromycin, or kanamycin sulfate) may be ordered to decrease bacteria in the intestine and help prevent postoperative...
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Chickenpox Vaccine
Encyclopedia entry from: Gale Encyclopedia of Children's Health: Infancy through Adolescence
...serum sodium ethylenediamine tetraacidic acid (EDTA) gelatin monosodium glutamate protein from the human cell line MRC-5 neomycin, an antibiotic phosphate buffers sodium chloride sucrose Effectiveness VZV is considered to be safe and 70 to 90 percent effective...
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