Research topic:liver

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liver

A Dictionary of Biology | 2004 | © A Dictionary of Biology 2004, originally published by Oxford University Press 2004. (Hide copyright information) Copyright

liver A large lobed organ in the abdomen of vertebrates that plays an essential role in many metabolic processes by regulating the composition and concentration of nutrients and toxic materials in the blood. It is made up of units called lobules, each of which is a roughly hexagonal structure consisting largely of hepatocytes arranged around a central vein. The liver receives the products of digestion dissolved in the blood via the hepatic portal vein and its most important functions are to convert excess glucose to the storage product glycogen, which serves as a food reserve; to break down excess amino acids to ammonia, which is converted to urea or uric acid and excreted via the kidneys; and to store and break down fats (see lipolysis). Other functions of the liver are (1) the production of bile; (2) the breakdown (detoxification) of poisonous substances in the blood; (3) the removal of damaged red blood cells; (4) the synthesis of vitamin A and the blood-clotting substances prothrombin and fibrinogen; and (5) the storage of iron (see ferritin).

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Related entries from encyclopedias, dictionaries, and thesauruses

Liver Transplantation
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Liver Transplantation Definition Liver transplantation is a surgery that removes a diseased liver and replace it with a healthy donor liver. Purpose The liver is the body's principle chemical factory. It receives all nutrients, drugs, and...
Liver Disease
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. ...that about 25 million Americans experience a liver-related disease each year. Individuals cannot live without a functioning liver. The ability to transplant livers is improving, liver transplantation is not nearly as common or...
Liver Function Tests
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Liver Function Tests Definition Liver function tests, or LFTs, include tests for bilirubin, a breakdown...a protein byproduct that is normally converted into urea by the liver before being excreted by the kidneys. LFTs also commonly include...
Liver Cancer
Encyclopedia entry from: Gale Encyclopedia of Cancer Liver cancer Definition Liver cancer is a form of cancer with a high mortality rate. Liver cancers can be classified into two types. They are either primary, when the cancer starts in the liver itself, or metastatic, when the cancer has spread...
Liver Biopsy
Encyclopedia entry from: Gale Encyclopedia of Surgery: A Guide for Patients and Caregivers Liver biopsy Definition A liver biopsy is a medical procedure performed to obtain a small piece of liver tissue for diagnostic testing. The sample is examined under a microscope by a pathologist, a doctor who specializes in the effects of disease...

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