Anne of Brittany (1477–1514; Ruled 1491–1498, 1499–1514)
ANNE OF BRITTANY (1477–1514; ruled 1491–1498, 1499–1514)
ANNE OF BRITTANY (1477–1514; ruled 1491–1498, 1499–1514), queen of France. Duchess of Brittany and twice queen of France, Anne was the daughter of Francis II (1435–1488) of Brittany and Marguerite de Foix. She was eleven when a French army defeated her father in the Fools' War in August 1488. Francis died a month after, and Anne inherited the duchy as the elder of his two daughters. Her hand in marriage became a valuable prize. In hopes of preventing the duchy from falling under direct French rule, Archduke Maximilian of Austria (later Holy Roman emperor; ruled 1493–1519), King Henry VII of England, and King Ferdinand of Aragon supported her against the French, and she agreed to marry Maximilian. In 1490 they were married by proxy, but the archduke delayed coming to Brittany. In 1491 French forces entered her capital of Rennes, and she was pressed to marry Charles VIII (ruled 1483–1498) of France. Convinced by her confessor that she was free to marry him, Anne agreed to a marriage contract that stipulated she would have to marry Charles's successor in default of a son from their marriage. The marriage took place at Rennes in December 1491.
Anne's marriage contract with Charles also stipulated that she would remain the ruling duchess of Brittany, and she always took a deep interest in its affairs while living at the French court, although it appears that she could not speak Breton. On several occasions she spent months away from her husband directing the affairs of her duchy. Those absences and that of her husband for sixteen months during the first French invasion of Italy (1494–1495) reduced the opportunities for Anne to become pregnant. She gave birth to a son, Charles Orland, a year after her marriage, but he died of measles at age three. Two more pregnancies resulted in a stillbirth and a son who died after five weeks.
When Charles VIII died suddenly in April 1498, Anne became a widow at age twenty-one. Her obligation to marry his successor, Charles's cousin Louis of Orléans (ruled 1498–1515), was complicated by his marriage to Jeanne of France, the daughter of Louis XI. Louis of Orléans requested an annulment from Pope Alexander VI on the grounds of coercion and nonconsummation. After his son Cesare Borgia was properly rewarded with French titles and treasure, Alexander granted the annulment. In January 1499 Anne and Louis XII were married, making her queen of France for a second time, the only woman for whom that was true. Their marriage contract stipulated that Brittany would continue to be governed separately from France and that it would go to the second son from the marriage or, in default of sons, the second daughter. In the absence of any children, it would go to Anne's closest relative. She was determined to maintain the duchy's autonomy from the French monarchy.
During her marriage to Louis, Anne was a key adviser to her husband, and she served as regent for him during his several Italian expeditions and a serious illness of 1505. The primary duty of the queen, however, was producing a male heir. In that respect Anne was unsuccessful. From at least five pregnancies, two daughters, Claude (born 1499) and Rénée (born 1510) alone survived. Anne strongly supported the betrothal of her young daughter Claude to Charles of Austria in 1503. She was sharply opposed to the proposed marriage between Claude and Francis of Angoulême (ruled 1515–1547), the successor to the French throne in default of any sons from Louis. Anne despised Francis's mother Louise
of Savoy (1476–1531) and was eager to maintain Brittany's autonomy, which she perceived would be easier to do with a foreign prince as its duke. Much to her anger, Louis wrote a will in 1505 that repudiated the marriage between Claude and Charles and required their daughter to marry Francis. It was only after Anne's death in 1514 that Claude married Francis. Louis quickly remarried, to Mary Tudor, Henry VIII's sister, but he died in 1515 without having a child with her. Francis, Louis's son-in-law and cousin, became king, and he undid Anne's determined efforts to keep Brittany autonomous by making his heir its duke in 1534, thereby absorbing it into the royal domain.
Anne was a patron of artists and writers. Her most notable commission was for the splendid funeral monument for her father at Nantes.
See also Brittany ; Charles VIII (France).
BIBLIOGRAPHY
Bridge, John S. C. A History of France from the Death of Louis XI. 5 vols. Oxford, 1921–1936. A highly detailed history of France that covers Anne's lifetime.
Matarasso, Pauline. Queen's Mate: Three Women of Power in France on the Eve of the Renaissance. Brookfield, Vt., 2001. Study of Anne and two other powerful women of her era, Anne of Beaujeu and Louise of Savoy.
Frederic J. Baumgartner
Cite this article
Pick a style below, and copy the text for your bibliography.
BAUMGARTNER, FREDERIC J.. "Anne of Brittany (1477–1514; Ruled 1491–1498, 1499–1514)." Europe, 1450 to 1789: Encyclopedia of the Early Modern World. The Gale Group Inc. 2004. Encyclopedia.com. 29 Nov. 2009 <http://www.encyclopedia.com>.
BAUMGARTNER, FREDERIC J.. "Anne of Brittany (1477–1514; Ruled 1491–1498, 1499–1514)." Europe, 1450 to 1789: Encyclopedia of the Early Modern World. The Gale Group Inc. 2004. Encyclopedia.com. (November 29, 2009). http://www.encyclopedia.com/doc/1G2-3404900046.html
BAUMGARTNER, FREDERIC J.. "Anne of Brittany (1477–1514; Ruled 1491–1498, 1499–1514)." Europe, 1450 to 1789: Encyclopedia of the Early Modern World. The Gale Group Inc. 2004. Retrieved November 29, 2009 from Encyclopedia.com: http://www.encyclopedia.com/doc/1G2-3404900046.html
Learn more about citation styles
|
Uric Acid, Type 2 Diabetes, and Cardiovascular Diseases: Fueling the Common Soil Hypothesis?
Magazine article from: Clinical Chemistry; 2/1/2008; ; 700+ words
; Uric acid is the final oxidation product...diseases, and most notably uric acid is causally involved in...across extreme quintiles of uric acid in multivariable analyses...that part of the effect of uric acid on the incidence of diabetes...
|
|
Preparation of Uric Acid Standard Stock Solution
Magazine article from: Clinical Chemistry; 11/1/2006; ; 665 words
; To the Editor: For measurement of uric acid in serum, calibrators of known concentration...be prepared in a suitable solvent. Uric acid is virtually insoluble in water...hydroxide as the solvent for dissolving uric acid at a molar ratio of ammonium hydroxide...
|
|
Associations of uric acid with polymorphisms in the [delta]-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers.(Research)
Magazine article from: Environmental Health Perspectives; 11/1/2005; ; 700+ words
; ...research suggests that uric acid may be nephrotoxic...associated with higher uric acid in those with the...lead exposure, uric acid, vitamin D receptor...and increased uric acid levels (Lin et al...literature suggests that uric acid may be nephrotoxic...
|
|
Uric Acid May Help Reduce Effects of Spinal Cord Injury, Jefferson Researchers Find.
News Wire article from: Ascribe Higher Education News Service; 2/14/2005; 700+ words
; ...Increasing levels of uric acid, a metabolic breakdown...rats that were given uric acid. "The injury causes a...two or three joints. The uric acid-treated rats recovered...feasible to give someone uric acid immediately and raise levels...
|
|
Perchloric Acid Treatment To Stabilize Uric Acid Concentrations in Blood Samples of Patients Receiving Uric Acid Oxidase (Rasburicase) Therapy
Magazine article from: Clinical Chemistry; 2/1/2007; ; 700+ words
; ...the Editor: Sample handling requirements for uric acid analysis during recombinant uric acid oxidase (rasburicase, Sanofi-Synthelabo...Following the manufacturer's instructions, uric acid concentration was 83 mol/L, compared to 95...
|
|
Associations among lead dose biomarkers, uric acid, and renal function in Korean lead workers.(Research)
Magazine article from: Environmental Health Perspectives; 1/1/2005; ; 700+ words
; ...Recent research suggests that both uric acid and lead may be nephrotoxic at lower...Fructuoso et al. 2002; Vaziri 2002). Uric acid is also a nephrotoxicant, and increasing...lead biomarkers were associated with uric acid and whether uric acid levels were...
|
|
High serum uric acid linked to atherosclerosis.(CARDIOVASCULAR MEDICINE)
Magazine article from: Family Practice News; 8/1/2009; ; 700+ words
; ...asymptomatic adults with elevated serum uric acid levels had a significantly increased...into quartiles based on their serum uric acid levels. The highest quartile level...10 had gout, although with serum uric acid levels this high many more would...
|
|
Sample Preparation in Patients Receiving Uric Acid Oxidase (Rasburicase) Therapy
Magazine article from: Clinical Chemistry; 8/1/2003; ; 700+ words
; ...patient who received the recombinant uric acid oxidase Rasburicase (Sanofi-Synthelabo...sample handling requirements for uric acid analysis. Rasburicase is a...medications may cause artefactually low uric acid concentrations, as documented in...
|
|
Plasma Uric Acid and the Risk of Type 2 Diabetes in a Chinese Community
Magazine article from: Clinical Chemistry; 2/1/2008; ; 700+ words
; ...studies of an association between uric acid and diabetes risk is limited. We...renal disease (3,4), the role of uric acid in diabetes risk remains controversial...biochemical biomarkers, including lipids, uric acid, and glucose, and assessed renal...
|
|
Uric acid may raise CKD risk: large study provides more epidemiologic evidence of an association.
Magazine article from: Renal & Urology News; 7/1/2008; ; 700+ words
; ...found that higher levels of uric acid are associated with an increased...epidemiologic evidence linking uric acid to development of renal...found that elevated serum uric acid levels are a modest...Each 1 mg/dL rise in uric acid was associated with a 7...
|
|
Uric Acid Tests
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...measure the level of kidney functioning. Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. (Nucleic acids are the building blocks of DNA.) Uric acid is made in the liver and excreted by the...
|
|
uric acid
Book article from: The Columbia Encyclopedia, Sixth Edition
uric acid , white, odorless, tasteless...to form purines and finally uric acid; these so-called uricotelic...normal human blood. The pure acid is obtained from guano and...which is then evaporated. If uric acid is present, murexide...
|
|
Lactic Acid
Encyclopedia entry from: The Gale Encyclopedia of Science
...the bloodstream and the lactic acid is converted to carbon dioxide...which are exhaled. If lactic acid levels in the bloodstream rise...x2014; combinations of acids, salts, and bases that maintain...metabolize, or break down, lactic acid is decreased significantly by...can also lead to a buildup ...
|
|
Anti-Hyperuricemic Drugs
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...hyperuricemia, the state of having too much uric acid in the blood. Purpose Anti-hyperuricemic drugs decrease the levels of uric acid in the blood, either by increasing...allopurinol decreases the amount of uric acid that is produced (and may help prevent...
|
|
Gout Drugs
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...Purpose Gout is a disease in which uric acid, a waste product that normally passes...wine, may increase the amount of uric acid in the body and may interfere with...conditions that result from excess uric acid) may need to limit the amount...
|