Effects of aqueous extracts of Halimeda incrassata (Ellis) Lamouroux and Bryothamnion triquetrum (S.G. Gmelim) Howe on hydrogen peroxide and methyl mercuryinduced oxidative stress in GT1-7 mouse hypothalamic immortalized cells.

From: Phytomedicine: International Journal of Phytotherapy &Phytopharmacology | Date: January 1, 2003| Author: | Copyright information

Summary

The current investigation focuses attention on the neuroprotective and antioxidant properties of aqueous extracts from Halimeda incrassata (Hi) and Bryothamniom triquetrum (Bt) in the mouse immortalized hypothalamic GT1-7 cell line. Under basal oxidative conditions, Hi extract reduces intracellular reactive oxygen species production, as assessed by 2'7'-dichlorofluorescein fluorescence, while Bt extract does not contribute to basal ROS generation. Both extracts, at concentrations higher than 0.20 mg/ml, exert protection against hydrogen peroxide-mediated cell death, ...

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