In ovo exposure to o,p'-DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes). (Research). From: Environmental Health Perspectives | Date: January 1, 2003| Author: Papoulias, Diana M.; Villalobos, Sergio A.; Meadows, John; Noltie, Douglas B.; Giesy, John P.; Tillitt, Donald E. | COPYRIGHT 2003 National Institute of Environmental Health Sciences. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

Despite being banned in many countries, dichlorodiphenyltrichloroethane (DDT) and its metabolites dichlorodiphenyldichloroethylene (DDE) and dichlorodiphenyldichloroethane (DDD) continue to be found in fish tissues at concentrations of concern. Like o,p'-DDT, o,p'-DDE is estrogenic and is believed to exert its effects through binding to the estrogen receptor. The limited toxicologic data for o,p'-DDE suggest that it decreases fecundity and fertility of fishes. We conducted an egg ...