Cadmium and lead in blood in relation to low bone mineral density and tubular proteinuria. (Research Articles).

Environmental Health Perspectives | July 1, 2002| | Copyright

Long-term exposure to cadmium may cause kidney and bone damage. Urinary cadmium is commonly used as the dose estimate for the body burden of cadmium. However, elevated levels of cadmium in the urine may reflect not only high levels of cadmium dose but also renal dysfunction. In this study we used blood cadmium as the dose estimate. In addition, we analyzed blood lead. We examined 479 men and 542 women, ages 16-81 years, who were environmentally or occupationally exposed to cadmium and lead. We used urinary protein [[alpha].sub.1]-microglobulin as a marker for tubular ...

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