Calcium channel blockers for treatment of hypertension. From: American Family Physician | Date: May 1, 1990 | COPYRIGHT 1990 American Academy of Family Physicians. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information) Copyright information

The three first-generation calcium channel blockers available in the United States-verapamil, nifedipine and diltiazem-have been widely used in the treatment of angina. Because of their efficacy and relatively mild side effects, calcium channel blockers were recommended as initial monotherapy for hypertension in the 1988 report of the Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure. Kaplan reviews the mode of action of calcium channel blockers, similarities and differences between the drugs, age and race differences in drug response, the ...

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