The safety and efficacy of high-dose chromium. (High-Dose Chromium).

From: Alternative Medicine Review | Date: June 1, 2002| Author: Lamson, Davis W.; Plaza, Steven M. | Copyright information

Abstract

The data on the standards for chromium requirements and the safety of various chromium compounds and doses are reviewed. The 350-fold difference between the acceptable daily intake and the calculated reference dose for humans of 70 mg per day seems without precedent with respect to other nutritional minerals. Previous claims of mutagenic effects of chromium are of questionable relevance. While studies have found DNA fragmentation (clastogenic effects) by chromiu...

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