It may enhance alertness, boost physical performance and even help burn fat, but taken excessively, caffeine can bring on a case of the jitters that overwhelms any of its benefits. Everyone has a different level of tolerance, so you need to monitor how your caffeine intake affects your energy level, sleep patterns, and mood. As a general guideline, once a 185-pound man exceeds about 250 to 350 milligrams a day, the cup overflows, and you may encounter such side effects as elevated blood pressure, heartburn, diarrhea, irritability and sleep loss. How do you know if you're over ...

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