Focal orchitis in undescended testes: discussion of pathogenetic mechanisms of tubular atrophy.

From: Archives of Pathology & Laboratory Medicine | Date: January 1, 2002| Author: | Copyright information

* Objective.--To evaluate seminiferous epithelium lesions in adult cryptorchid testes showing lymphoid infiltrates in seminiferous tubules and interstitium (ie, focal orchitis). Also, to consider the possible role of this lesion in the etiology of tubular atrophy.

Methods.--We performed a histopathologic study of the cryptorchid testes and adjacent epididymides removed from 50 adult men who had not been previously treated for cryptorchidism. The study included morphologic and semiquantitative evaluation of seminiferous tubule pathology (according to germ cell numbers), Sertoli cell ...

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