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Differential effects of two lots of Aroclor 1254: congener-specific analysis and neurochemical end points. (Articles).

From: Environmental Health Perspectives  |  Date: 11/1/2001  |  Author: Birnbaum, Linda S.; Burgin, Deborah E.; Derr-Yellin, Ethel C.; Kannan, Narayanan; Kodavanti, Prasada Rao S.; Tilson, Hugh A.; Ward, Thomas R.; Yamashita, Nobuyoshi

Aroclor 1254 is a widely studied commercial polychlorinated biphenyl (PCB) mixture which, by definition, contains 54% chlorine by weight. Recent reports indicate substantial differences in the congener composition among Aroclor lots and hence their biologic effects. We designed the current study to compare the effects of two lots of Aroclor 1254 (lots 6024 and 124-191). We analyzed these two lots for PCB congeners, polychlorinated dibenzofurans (PCDFs), polychlorinated naphthalenes ...

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