ISOLATION OF PHAGE P1 REGULATORY MUTANTS.

From: Georgia Journal of Science | Date: June 22, 2001| Author: Rivera, Sheila D. | Copyright information

ABSTRACT

A repressor protein of bacteriophage P1, encoded by the c1 gene, is responsible for maintaining P1 prophage in the lysogenic state. The product of this gene, c1 repressor protein, binds to specific sites along the P1 genome and allows phage survival by preventing cell lysis. To better understand the genetics of P1, it is important to identify mutations within the c1 gene that prevent this lysogeny maintenance. This study identifies a point mutation at nucleotide...

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