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Molecular Epidemiology of Serogroup A Meningitis in Moscow, 1969-1997.

From: Emerging Infectious Diseases  |  Date: 5/1/2001  |  Author: Achtman, Mark; Brieske, Norbert; Koroleva, Irina S.; Kostyukova, Natalya N.; Kusecek, Barica; Morelli, Giovanna; Platonov, Alexander E.; Schuurman, Ilse G.A.; van der Ende, Arie; Zhu, Peixuan; Zurth, Kerstin

Molecular analysis of 103 serogroup A Neisseria meningitidis strains isolated in Moscow from 1969 to 1997 showed that four independent clonal groupings were responsible for successive waves of meningococcal disease. An epidemic from 1969 to the mid-1970s was caused by genocloud 2 of subgroup III, possibly imported from China. Subsequent endemic disease through the early 1990s was caused by subgroup X and then by subgroup VI, which has also caused endemic disease elsewhere in eastern ...

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