Hereditary Cancer Syndromes.

From: Archives of Pathology & Laboratory Medicine | Date: January 1, 2001| Author: Frank, Thomas S. | Copyright information

Objective.--To summarize the biological basis, clinical implications, identification, and medical management of syndromes associated with increased risk of common adult cancers.

Data Sources.--Recent studies and data available from molecular and clinical analysis of genes responsible for autosomal-dominant inheritance of cancer risk.

Data Synthesis.--Several hereditary cancer syndromes have been identified for which there are increasingly effective diagnostic and managemen...

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