Availability and Use of Parenteral Quinidine Gluconate for Severe or Complicated Malaria.(recommendation for hospitals to improve their stocking of quinidine gluconate)(quinidine gluconate)(Brief Article)

Morbidity and Mortality Weekly Report | December 22, 2000 | Copyright

Since 1991, quinidine gluconate, a class la anti-arrhythmic agent, has been the only parenteral antimalarial available for use in the United States [1]. It is indicated for the treatment of patients with life-threatening Plasmodium falciparum malaria [2], including those who cannot tolerate oral therapy, have high-grade parasitemia, or have complications (e.g., cerebral malaria or acute renal failure) [3,4].

The limited availability of and delays in obtaining quinidine gluconate have contributed to adverse patient outcomes [5-7]. As newer anti-arrhythmics have ...

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