 "Rocky Mountain News (Denver, CO)")
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'DISCOVERY' CHARTS A HISTORY OF WORLD TRAVEL AS SUBJUGATION.(SPOTLIGHT)(Review)
Rocky Mountain News (Denver, CO)
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February 18, 1996
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COPYRIGHT 1996 Rocky Mountain News. All rights reserved. Reproduced with the permission of Dialog LLC by Gale Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.
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Byline: DAN WHIPPLE
Back in the Vietnam era, there was bumper sticker humor that went something like this: "Join the Army. Visit exotic places. Meet interesting people. And kill them."
OK. Maybe humor isn't the right word. In Shores of Discovery, Eric Leed explains why. When modern humans travel, they are likely to undertake a romantic vacation in Crete, or immerse themselves in the carnival rush of Las Vegas.
In the not-too-distant past, Leed writes, travel consisted largely of perilous military expeditions designed to subjugate and enslave ...
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Mutant cytosine deaminase is an effective prodrug converter.
Newspaper article from: Drug Week
; ...com & NewsRx.net) -- Mutant cytosine deaminase is an effective prodrug converter...Escherichia coli gene, codA, encodes cytosine deaminase and is introduced into cancer...investigators in the United States report. "Cytosine deaminase converts 5-FC into cytotoxic...
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Cytosine Arabinoside Substitution Decreases Transcription Factor-DNA Binding Element Complex Formation
Magazine article from: Archives of Pathology & Laboratory Medicine
; ...The pyrimidine nucleoside analog, cytosine arabinoside (Ara-C), is an effective...leukemia. The phosphorylated triphosphate, cytosine arabinoside triphosphate, competes with...determine if the substitution of Ara-C for cytosine in double-stranded oligonucleotides...
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A New Cytosine-Cytosine Cross-Link
Magazine article from: Photochemistry and Photobiology
; ...interest. Wang and coworkers previously characterized a cytosine-cytosine cross-link formed when the dinucleoside monophosphate...and coworkers (pp. 209-215) describe a second cytosine-cytosine cross-link lesion, which is formed in...
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SYNTHESIS OF N^sup 4^-SUBSTITUTED DERIVATIVES OF 1-[2-(PHOSPHONOMETHOXY)ETHYL]CYTOSINE AND ITS DIISOPROPYL ESTER AS A MODEL REACTION FOR THE SYNTHESIS OF N^sup 4^-SUBSTITUTED DERIVATIVES OF CIDOFOVIR
Magazine article from: Collection of Czechoslovak Chemical Communications
; ...2-(phosphonomethoxy)ethyl]cytosine (1) and its diisopropyl ester (2...amines the reaction failed. Keywords: Cytosine modification; Antivirals; Cidofovir...3hydroxy-2-(phosphonomethoxy)propyl]cytosine (CAS 113852-37-2, HPMPC, Cidofovir...
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Cytosine Deaminase/5-Fluorocytosine-Based Vaccination Studied.(Brief Article)(Statistical Data Included)
Newspaper article from: Gene Therapy Weekly
; ...suggested recent research from France. "The cytosine deaminase gene of Escherichia coli converts...We analyzed the efficacy of using cytosine deaminase-bearing cancer cells as an...of the National Cancer Institute ("Cytosine deaminase/5-fluorocytosine-based...
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Energetics of Cytosine Singlet Excited-State Decay Paths-A Difficult Case for CASSCF and CASPT2[dagger]
Magazine article from: Photochemistry and Photobiology
; ...deactivation paths for singlet excited cytosine are calculated at the CASPT2//CASSCF...sub-picosecond range. In the case of cytosine, the decay in the gas phase was first...identified for the decay of singlet excited cytosine to the ground state (11-16). A first...
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Neutropenic colitis after treatment of acute myelogenous leukemia with idarubicin and cytosine arabinoside
Magazine article from: Mayo Clinic Proceedings
; ...gastrointestinal toxic effects of idarubicin and cytosine arabinoside combination therapy in patients...diagnosed AML receiving idarubicin and cytosine arabinoside combination therapy. Using...78 patients receiving idarubicin and cytosine arabinoside for treatment of AML, 65...
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Yeast Cytosine Deaminase Improves Radiosensitization and Bystander Effect.
Newspaper article from: Cancer Weekly
; ...fluorocytosine (5-FC) can be enhanced by using yeast cytosine deaminase instead of bacterial cytosine deaminase (bCD), suggests a study from the...strategy is limited by the inefficiency of cytosine deaminase (CD)-catalyzed conversion of...
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Early earth may have had two key RNA bases. (pyrimidine bases of cytosine and uracil may have been created in tidal pools)(Brief Article)
Magazine article from: Science News
; ...building blocks--adenine, guanine, cytosine, and uracil--formed first. Although...also noted that the pyrimidine bases, cytosine and uracil, do not. Now, Michael P...prebiotic route" for the synthesis of cytosine and uracil. "What we're envisioning...
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A Molecular Dynamics Study of the Ligand Release Path in Yeast Cytosine Deaminase
Magazine article from: Biophysical Journal
; ABSTRACT Yeast cytosine deaminase, a zinc metalloenzyme, catalyzes the deamination of cytosine to uracil. Experimental and computational...with one much more favored than the other. Cytosine is pushed out of the active site by a restraint...
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