Human autoimmune diseases: Progress in clinical laboratory tests.

Medical Laboratory Observer | October 1, 2000| | Copyright

Severe derangements of the human immune system and its associated network can cause more than 40 autoimmune diseases in 5% to 10% of the general population. These diseases injure various organs and tissues of the endocrine, neuromuscular, hematopoietic, cardiopulmonary, gastrointestinal, and dermatologic systems. [1,2] Because of complex interactions among multiple genetic, immunologic, and environmental factors, these autoimmune diseases are heterogeneous in both etiology and the associated clinical and histopathologic manifestations. [3,4]

In industrialized ...

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