Occurrence of Tris(4-chlorophenyl)methane, Tris(4-chlorophenyl)methanol, and Some Other Persistent Organochlorines in Japanese Human Adipose Tissue.

From: Environmental Health Perspectives | Date: July 1, 2000| Author: Hata, Jun-ichi; Minh, Tu Binh; Tanabe, Shinsuke; Watanabe, Mafumi; Watanabe, Shaw; Yamada, Taketo | Copyright information

Tris(4-chlorophenyl)methane (TCPMe) and tris(4-chlorophenyl)methanol (TCPMOH) are among the most recently identified environmental contaminants. Despite their widespread contamination in the marine environment, human exposure to these compounds remains relatively unknown. We determined the concentrations of TCPMe, TCPMOH, and other persistent organochlorines such as polychlorinated biphenyls (PCBs), DDT and its metabolites, hexachlorocyclohexane isomers, hexachlorobenzene, and chlo...

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and journal articles from HighBeam Research

Relationship between human adipose tissue agouti and fatty acid synthase (FAS)
The Journal of Nutrition ; Relationship between Human Adipose Tissue Agouti and Fatty Acid Synthase (FAS)1,2 ABSTRACT The human homologue of the murine obesity gene, agouti, is expressed in adipose tissue. We have shown that recombinant agouti protein regulates adipocyte lipogenesis and lipolysis coordinately and promotes
Occurrence of Tris(4-chlorophenyl)methane, Tris(4-chlorophenyl)methanol, and Some Other Persistent Organochlorines in Japanese Human Adipose Tissue.
Environmental Health Perspectives ; Tris(4-chlorophenyl)methane (TCPMe) and tris(4-chlorophenyl)methanol (TCPMOH) are among the most recently identified environmental contaminants. Despite their widespread contamination in the marine environment, human exposure to these compounds remains relatively unknown. We determined the
The Human Fatty Acid Synthase Gene and De Novo Lipogenesis Are Coordinately Regulated in Human Adipose Tissue1
The Journal of Nutrition ; ABSTRACT Despite its potential importance in obesity and related disorders, little is known about regulation of lipogenesis in human adipose tissue. To investigate this area at the molecular and mechanistic levels, we studied lipogenesis and the regulation of 1 of its core enzymes, fatty acid
Specific accumulation and elimination kinetics of tris(4-chlorophenyl)methane, tris(4-chlorophenyl) methanol, and other persistent organochlorines in humans from Japan. (Articles).
Environmental Health Perspectives ; We examined human adipose tissue, liver, and bile from humans in Japan to understand the contamination status, specific accumulation, and elimination of two newly identified environmental contaminants, tris(4-chlorophenyl)methane (TCPMe), tris(4-chlorophenyl)methanol (TCPMOH), and other persistent
Gene Expression Profiling in Human Preadipocytes and Adipocytes by Microarray Analysis1,2
The Journal of Nutrition ; ABSTRACT Uncontrolled expansion of adipose tissue leads to obesity, a public health epidemic affecting >30% of adult Americans. Adipose mass increases in part through the recruitment and differentiation of an existing pool of preadipocytes (PA) into adipocytes (AD). Most studies investigating
Insulin increases lipogenic enzyme activity in human adipocytes in primary culture
The Journal of Nutrition ; Fatty acid and triacylglycerol synthesis for energy storage are regulated in response to hormonal and nutritional states. Adipose tissue is the major site far energy storage and plays an important role in maintaining glucose homeostasis. Abnormalities in hormonal and nutritional regulation of this
Is EPA wearing too many HATS? (Environmental Protection Agency tries to phase out Human Adipose Tissue Survey)
Science News ; Is EPA wearing too many HATS? When the Reagan administration released its budget last month, it withheld a decision on how much to allocate for the Environmental Protection Agency's Human Adipose Tissue Survey (HATS). Begun in 1967, it surveys not only which toxic substances (such as pesticides)
Toxic chlorobiphenyls in adipose tissue and whole blood of an occupationally/accidentally exposed man and the general population.
Archives of Environmental Health ; Human exposure to polychlorinated biphenyls (PCBs) occurs through different routes. The general public is exposed via dietary intake from fish and other contaminated foods.[1] Dermal and respiratory exposures to PCBs occur in workers involved in the production of capacitors and transformers.[2]
Arachidonic Acid in Adipose Tissue Is Associated with Nonfatal Acute Myocardial Infarction in the Central Valley of Costa Rica1
The Journal of Nutrition ; ABSTRACT Arachidonic acid (AA), a precursor of prothrombotic eicosanoids, is potentially atherogenic, but epidemiologic data are scarce. We evaluated the hypothesis that increased AA in adipose tissue is associated with increased risk of nonfatal acute myocardial infarction (MI), and if so, whether
Somatotropin regulates adipose tissue metabolism in neonatal swine
The Journal of Nutrition ; Somatotropin Regulates Adipose Tissue Metabolism in Neonatal Swine1'2'3 ABSTRACT Somatotropin (ST) reduces lipid deposition in growing and adult animals, but its effect in neonatal pigs is not clear. In this study, we tested the hypothesis that ST inhibits lipid deposition in neonatal pig adipose