How fourteen anti-HIV drugs could provide more bang for the buck.

From: Research Initiative/Treatment Action! | Date: June 1, 2000| Author: Martinez, L. Joel | Copyright information

Background. Controlling HIV, at least in the short run, requires that persons infected with the virus be fully suppressed or so goes the theory. Yet the point of suppression keeps moving with time. In the early days of viral load using bDNA (branched DNA), patients were told that a viral load of less than 10,000 copies/mL constituted an undetectable viral load. Translated to PCR (polymerase chain reaction), the test more commonly used today, that figure would be a viral load of 20,...

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and journal articles from HighBeam Research

HIV Resistance: Data and spin.(overview on drug-resistant HIV infection)
AIDS Treatment News ; ... fact, as one of the researchers noted to AIDS Treatment News, the good news is that treatments are still saving lives despite viral ... at least one antiretroviral. There was confusion in news reports over whether resistance was found in 78% of ...
BODY : FITNESS & EXERCISE VIRAL LOAD VALUABLE BAROMETER IN AIDS CASES.(L.A. LIFE)
Daily News (Los Angeles, CA) ; Byline: Laura Beil Dallas Morning News Some people infected with the AIDS virus spend a lot of time watching numbers rise and fall. A T-cell count, long viewed as the ...
Questions about HIV Causing AIDS? Viral Load and T-Cell (CD4) Counts: Why They Really Matter.
AIDS Treatment News ; If you are being treated for HIV or AIDS, your doctor uses a number of blood tests to check how you're doing. One of the most important tests measures viral load, the amount of HIV in your blood. Another very important test counts your CD4 cells, sometimes called T-cells. CD4 cells are a key part
Africa Studies Raise AIDS Vaccine Hopes; Viral Load, Chances of Infection Linked
The Washington Post ; A low concentration of the AIDS virus in the bloodstream greatly decreases the chance that an infected man or woman will transmit the disease to a heterosexual partner, according to two studies from Africa presented at a scientific meeting here. That observation raises the possibility that an
Viral load versus p24 antigenaemia in human immunodficiency virus infected patients
British Journal of Biomedical Science ; Monitoring human immunodeficiency virus type-1 (HIV- 1) RNA levels is important in the management of patients with HIV-1 infection, and its use is well accepted During the past three years, its incorporation in the attendance routine has been strengthened in our medical scene. There is no need to
Moderate HIV viral load the most infectious.(AIDS briefs)(Human immunodeficiency virus)
CME: Your SA Journal of CPD ; In what appears to be a paradox, research has shown that HIV may have evolved so that the average viral load set-point--around 33 000 copies/ml--seen in most untreated people during chronic infection is finely balanced between being optimal for HIV transmission and optimal for host survival
Don't flip over blips. (Bottom Lines).(viral load)(Brief Article)
HIV Treatment: ALERTS! ; In a recent paper published in The Journal of the American Medical Association (286:2, p. 171, 2001), researchers analyzed the frequency of temporary, low-level increases in viral load ( blips ) and whether such episodes could predict failure of anti-HIV drugs. The researchers looked back at 2
Subclinical Plasmodium falciparum infection and HIV-1 viral load.(Letter to the editor)
Emerging Infectious Diseases ; To the Editor: Studies indicate that Plasmodium falciparum infection increases HIV replication in adults (1,2). Although malaria-related illness and death are more common in children, and HIV-1 generally progresses faster in children than in adults (3,4), to our knowledge the effect of intermittent
Early viral load predicts treatment success.(Treatment News)(Brief Article)
HIV Treatment: ALERTS! ; The sooner you know if your HIV treatment is working, the better. Continuing an ineffective HIV treatment regimen could not only allow your HIV to progress, but also allow drug resistance to develop. A study published in the Journal of Acquired Immune Deficiency Syndromes (37:1, p. 1155, 2004)
Viral load: small change by sixth day of treatment can often predict poor response.(protease inhibitor evaluation)
AIDS Treatment News ; A U.S. National Institutes of Health study of 124 pediatric and adult patients taking protease inhibitors for the first time found that the change in viral load in the first six days of the treatment was able to predict many cases of poor response of the regimen by week 12. Therefore treatment