The Conundrum of Early HIV Infection. From: American Family Physician | Date: August 1, 1999| Author: | COPYRIGHT 1999 American Academy of Family Physicians. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

On the surface, it seems reasonable to advise physicians to suspect early human immunodeficiency virus (HIV) infection when clinically indicated and to be prepared to intervene with antiretroviral therapy. However, this premise is fraught with pitfalls and challenges for physicians on the front lines of care.

Exactly who should be tested, and when? If physicians only test the highest-risk patients, the majority of patients with early HIV infection will be missed. Risk factors do not reliably discriminate between those who might be infected and those who are not infected.

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