Diagnostic Markers for Detection of Myocardial Infarction.

From: American Family Physician | Date: July 1, 1999 | Copyright information

Only 10 to 15 percent of patients who present with acute chest pain have a myocardial infarction (MI). Symptoms cannot be used to differentiate those who have had an MI from those who have not. Further, the electrocardiogram is diagnostic for myocardial ischemia in only 40 percent of patients. Cardiac enzyme assays have formed the basis for making this critical determination. Unfortunately, the standard creatine kinase-MB (CK-MB) assay is not reliable in excluding infarction until 10 to 12 hours after the onset of chest pain. Earlier diagnosis would have very specific advantages ...

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