Trypanosoma cruzi Pyrrho, A.S.; Moraes, J.L.C.; Pecanha, L.M.T.; Gattass, C.R. "Trypanosoma cruzi: IgG1 and IgG2b Are the Main Immunoglobulins Produced by Vaccinated Mice." Parasitology Research, April 1998;84(4):333-337.

Vaccine Weekly | June 8, 1998 | Copyright

According to the authors' abstract of an article published in Parasitology Research, "Mice vaccinated with CL-14, a non-infective and non-pathogenic clone isolated from Trypanosoma cruzi CL strain, become protected against lethal challenge by infective trypomastigotes. It has been shown that animals infected with T. cruzi show polyclonal activation of B lymphocytes with an early production of several non-specific immunoglobulins. Vaccinated mice, however, have an ...

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