Spotted vaccine to follow? (research on vaccine against Rocky Mountain spotted fever)

From: Science News | Date: January 17, 1987 | Copyright information

Spotted vaccine to follow?

Using cloning and recombinant DNA techniques, microbiologistsat the National Institute of Allergy and Infectious Diseases' Rocky Mountain Laboratories in Hamilton, Mont., have produced a possible vaccine against Rocky Mountain spotted fever. Caused by the bacterium Rickettsia rickettsii, the tick-borne disease destroys cells of the vascular system, leading to low blood volume and fluid-swollen tissues.

Members of the Hamilton team recently described protectionagainst the disease in mice, using antibodies against two surface antigens of R. ...

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