New virology data have been reported by scientists at World Health Organization.

Virus Weekly | November 17, 2009 | Copyright

According to a study from Melbourne, Australia, "To identify mutations that can arise in highly pathogenic A(H5N1) viruses under neuraminidase inhibitor selective pressure, two antigenically different strains were serially passaged with increasing levels of either oseltamivir or zanamivir. Under oseltamivir pressure, both A(H5N1) viruses developed a H274Y neuraminidase mutation, although in one strain the mutation occurred in combination with an I222M neuraminidase mutation."

"The H274Y neuraminidase mutation reduced oseltamivir susceptibility significantly (900- to ...

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