Research from University of Ottawa yields new findings on helicobacter pylori.

Biotech Week | November 4, 2009 | Copyright

According to a study from Ottawa, Canada, "Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens. To design an assay to rapidly detect these Mutations using rapid polymerase chain reaction and pyrosequencing, a novel method of 'sequencing by synthesis', and to test this assay with a collection of Canadian H pylori isolates."

"Forty-two H pylori isolates (24 clarithromycin-resistant, 18 ...

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