Data on chemical research detailed by I. Alonso and co-authors.

Chemicals & Chemistry | October 16, 2009 | Copyright

According to recent research published in the Journal of the American Chemical Society, "Gold(I) complexes featuring electron acceptor ligands such as phosphites and phosphoramidites catalyze the [4C+2C] intramolecular cycloaddition of allenedienes. The reaction is chemo- and stereoselective, and provides trans-fused bicyclic cycloadducts in good yields."

"Moreover, using novel chiral phosphoramidite-based gold catalysts it is possible to perform the reaction with excellent enantioselectivity. Experimental and theoretical data dismiss a cationic mechanism involving ...

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