Study results from University of Debrecen, Medical and Health Science Center update understanding of melanoma genetics.(Report)

Proteomics Weekly | October 12, 2009 | Copyright

Data detailed in 'Characterization of candidate gene copy number alterations in the 11q13 region along with BRAF and NRAS mutations in human melanoma' have been presented. According to a study from Debrecen, Hungary, "Amplification of the 11q13 chromosomal region is a common event in primary melanomas. Several candidate genes are localized at this sequence; however, their role in melanoma has not been clearly defined."

"The aim of this study was to develop an accurate method for determining the amplification pattern of six candidate genes that map to this amplicon ...

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