RWTH Aachen University publishes research in tissue engineering.

Blood Weekly | September 17, 2009 | Copyright

According to recent research from Aachen, Germany, "E-cyclins control the transition of quiescent cells into the cell cycle. Two E-cyclins, CcnE1 and CcnE2, have been described, but their specific contributions to cell cycle reentry in vivo are poorly understood."

"Liver regeneration following partial heparectomy is an excellent in vivo model for the study of cell cycle reentry of quiescent cells. We investigated the relevance of E-cyclins in directing resting hepatocytes into the cell cycle after partial hepatectomy using CcnE1 and CcnE2 knockout mice. Partial ...

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